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MSKReport Online Newsletter March 5, 2008
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MSK Report News

AAOS 2008: AAOS Researchers Provide New Look at Steroid-Induced Osteonecrosis
Steroid-induced osteonecrosis tends to resolve in SLE patients when the underlying disease is under control but tends to advance after SLE recurs. In patients with steroid-induced hip osteonecrosis, shoulder damage is likely to result in joint collapse within 15 years if not treated...

Pain: Fibromyalgia Patients With CDIP May Benefit From IVIg Therapy
Fibromyalgia (FM) patients with evidence of chronic inflammatory demyelinating polyneuropathy (CIDP) may benefit from treatment with intravenous immunoglubulin...

Arthritis: HLA-DRB1 Linked to Premature Cardiac Death in Some RA Patients
Patients with inflammatory polyarthritis (IP) who have the shared epitope (SE) alleles of the HLA-DRB1 gene are at increased risk of premature death from cardiovascular disease (CVD) and may benefit from treatment to improve their CV profile...

BioPharm Business: P&G Wins Patent Infringement Lawsuit for Osteoporosis Therapy Actonel; Teva to Appeal Court Ruling
Procter & Gamble announced that the US District Court of Delaware ruled in its favor in the patent infringement lawsuit the company filed against Teva Pharmaceuticals USA, Inc...

BioPharm Business: Karo Bio AB, Zydus Cadila to Develop Selective Glucocorticoid Receptor Modulators to Treat Inflammatory Diseases; Karo Reacquires Rights to SARMs From Radius
Karo Bio AB and Zydus Cadila announced a 3-year research collaboration to discover and develop novel, selective glucocorticoid receptor (GR) modulators for the treatment of inflammatory diseases...

BioPharm Business: Ipsen's Adenuric (febuxostat) for Chronic Hyperuricemia in Gout Receives Positive Opinion From CHMP; First Treatment Alternative in >40 Years if Approved by European Commission
Ipsen announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMEA) adopted a positive opinion for Adenuric (febuxostat) to treat chronic hyperuricemia for conditions in which urate deposition has already occurred...