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MSKReport Online Newsletter May 6, 2008
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With biweekly and special edition newsletters, Musculoskeletal Report is the top online resource for staying abreast of the most current and clinically relevant information in the field of musculoskeletal disease and treatment.

MSK Report provides cutting-edge scientific updates through in-depth interviews, on-location coverage of medical meetings, expert-led panel discussions, and live newscasts. With an editorial board of internationally recognized thought leaders, MSK Report is positioned to provide unparalleled quality news reporting with the highest level of credibility.

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Dr. John Crues presents "Evolution of MRI: A Formidable Radiological Tool for Musculoskeletal Disease" at the International Society of Extremity MRI in Rheumatology (ISEMIR) Conference



MSK Report News

Arthritis: FDA Adds "Black Box" Warning About Infections to Enbrel Label
FDA has heightened warnings on the prescribing information for etanercept with regard to serious infections and has warned clinicians to screen patients for latent TB before beginning treatment...

Bones: Icelandic and British Researchers ID Five New Osteoporosis Genes
New research spotlighting five genetic loci associated with bone mineral density (BMD) and fractures may provide insight into the biochemical pathways that underlie osteoporosis...

News Analysis: Genetic Information Nondiscrimination Act Passes Congress, Heads for White House
Both houses of Congress have passed legislation that bans discrimination in employment, insurance, and other areas based on an individual's genetic makeup, and the bill is expected to be quickly signed into law by President George W. Bush...

Consumer News: Younger People Getting Joint Replacements to Restore Active Lifestyles
A better understanding of joint mechanisms and new technologies allow younger adults to relieve pain with joint replacements...

BioPharm Business: Rigel's R788 (fostamatinib disodium) Slows Progression, Prolongs Survival in Murine Lupus Model; Phase II Lupus Clinical Trial Planned Later in 2008
Rigel's lead agent, R788 (fostamatinib disodium), an orally bioavailable spleen tyrosine kinase inhibitor, has successfully treated lupus-prone mice and significantly improved their survival...

BioPharm Business: Lexicon's RA Drug Candidate LX2931, Targeting S1P Lyase, Shows Positive Results in Phase 1a Clinical Trial; Dose-Dependent, Rapid-Onset Decrease in Circulating Lymphocytes Observed
Positive results were obtained from Lexicon's phase 1a clinical trial of LX2931, an orally-delivered, small molecule targeting sphingosine-1-phosphate (S1P) lyase for the treatment of RA and other autoimmune conditions...