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MSKReport Online Newsletter July 29, 2008
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Musculoskeletal Report provides cutting-edge scientific updates through in-depth interviews, on-location coverage of medical meetings, expert-led panel discussions, and live newscasts.

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MSK Report News

Autoimmunity: New High-Resolution Device Aids Finger MRI in Scleroderma
High-resolution magnetic resonance angiography (micro-MRA) can readily measure vascular disease of fingers in systemic sclerosis...

Arthritis: NHS TNF Inhibitor Restrictions Heighten Impact of Baseline DAS28 in RA
The British National Institute for Health and Clinical Excellence (NICE) guidelines for approving access to TNF inhibitors for patients with rheumatoid arthritis (RA) may be unnecessarily extending the period when steroids are not allowed and classifying >30% of patients as "nonresponders" who would not be allowed to continue anti-TNF treatment...

Consumer News: Complaints Undermine Hip Device
Sales of the Durom cup, an artificial hip socket, have been suspended following complaints by doctors of a high failure rate...

BioPharm Business: CEL-SCI Announces Positive Preclinical Results Using CEL-2000, a Chimeric Peptide with Bi-Functional Properties, as RA Vaccine
CEL-SCI Corp announced the discovery of CEL-2000, a novel peptide vaccine for the treatment of RA. Tests showed that CEL-2000 is equivalent or possibly superior to Enbrel in slowing disease progression and lessening symptoms in mice...

BioPharm Business: Chelsea Therapeutics Granted UK MHRA Approval to Begin Phase II Trial of Droxidopa, a Prodrug of Norepinephrine, in Fibromyalgia
Droxidopa, an orally active synthetic amino acid precursor of norepinephrine (NE), is converted by the body into norepinephrine and as a prodrug of NE, provides replacement therapy for NE deficiency...