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Found 36 result(s) FROM 1963 pages containing the term 'ankle sprain'.
Thursday Jul 23, 2009
Gene Therapy Cleared in RA Patient Death
The vector used in an RA gene therapy study did not cause the death of a patient who died during the trial...
Wednesday May 13, 2009
Persistent Sore Ankle Might Be Damaged Tendon
Physicians should consider peroneal tendon injury in patients with refractory lateral ankle pain...
Tuesday Feb 10, 2009
Each Osteoporotic Fracture Ups Death Risk
Women and men age 60 years or older who sustain a low-trauma osteoporotic fracture are at an increased risk of dying during the following 5 to 10 years...
Friday Dec 12, 2008
Cartilage Repair Moving from Bench to Bedside
Mosiacplasty may soon be the method of choice for orthopaedic surgeons treating small focal defects in cartilage, but stem cell-based cartilage repair is also moving stealthily down the pike...
Thursday Oct 09, 2008
Rheumatologists Usually on Target With Intra-Articular Injections, Even Without Ultrasound
New research shows that blind intra-articular injections (IAIs) in rheumatoid arthritis patients, done without ultrasound guidance, are accurate when performed by a trained rheumatologist. Blind injections into the ankle are the most unreliable, at 77% accuracy...
Thursday Sep 11, 2008
Total Ankle Replacements are Coming Into their Own—Finally
Total ankle replacements are expected to soon rival hip and knee replacements in design, function, and durability. Airbags and seatbelts contribute to growing demand…
Monday Sep 08, 2008
ACR Research and Education Foundation Grants Point to New Arthritis Research
New REF grants target RA immunotherapy, inflammation, bone erosions, PAD inhibition...
Thursday Aug 07, 2008
Doctors Seeing More Arthritis In Active Boomers
Early treatment can prevent long-term pain in active baby boomers that are now beginning to suffer from painful arthritis…
Thursday May 22, 2008
Ankle Osteoarthritis is Associated With Knee Osteoarthritis
Knee OA can change the alignment of the entire extremity, leading to degenerative changes in the ankle joint and the development of ankle OA...
Thursday Apr 24, 2008
S. pyogenes-Linked New-Onset Childhood Arthritis Differs in Severity, Duration, from Other Types
Up to 35% of children with new-onset arthritis test positive for S. pyogenes and have a different disease course than children with other forms of inflammatory arthritis; they do not need routine cardiology follow-up, according to a population-based study...
Wednesday Mar 12, 2008
Docs Seen as Clueless About What’s Afoot in RA
About 10% of RA patients develop some type of potentially debilitating foot ulceration, but management approaches are lagging behind…
Tuesday Feb 05, 2008
MGH Center is a Pioneer in Knee Repair
Physicians at the Massachusetts General Hospital sports medicine center are experimenting with new techniques for joint reconstruction in athletes...
Monday Dec 03, 2007
Targeted Genetics Announces That US FDA Removed Hold on Phase I/II Clinical Trial of tgAAC94 for Inflammatory Arthritis; Phase II Clinical Trial Protocol Design Underway
Targeted Genetics Corp announced that the US FDA removed the hold on the company's phase I/II clinical trial of tgACC94 for inflammatory arthritis, following the agency's review of the safety data thus far on all 127 subjects and all data from a fatal serious adverse event, which led to the death of a patient...
Tuesday Nov 13, 2007
Single Botulinum Toxin Injection Smooths Out OA Shoulder Pain
A single intra-articular injection of botulinum toxin type A relieved shoulder pain for a month in patients with refractory OA...
Tuesday Nov 13, 2007
Targeted Genetics Reports Positive Interim Phase I/II Results for tgAAC94 in Inflammatory Arthritis; Tests Indicate tgAAC94 Did Not Contribute to Immunosuppression Leading to Fatal SAE
Targeted Genetics Corp, a clinical-stage biotechnology company, announced that interim data from its phase I/II trial of tgAAC94 for inflammatory arthritis suggest that the investigational therapy showed improvement in patient-reported outcome measures...
Friday Nov 09, 2007
Control of Osteoclast Development Goes Awry in Gout
Patients with tophaceous gout have disordered osteoclast development partly due to the effect of uric acid crystals on bone marrow stromal cells...
Thursday Sep 20, 2007
Targeted Genetics Provides Update on its Inflammatory Arthritis Phase I/II Trial on Clinical Hold Following Patient Death; Data To Date Does Not Implicate Study Agent
Targeted Genetics Corp, a clinical-stage biotechnology company, reported on the public hearing conducted by the National Institutes of Health (NIH) recombinant DNA advisory committee (RAC), which reviewed the serious adverse event (SAE) reported by Targeted surrounding the death of a patient participating in the company's phase I/II trial of tgAAC94 for inflammatory arthritis...
Monday Aug 27, 2007
Harkness Dance Medicine Head Urges Clinicians to Prepare for the "High School Musical 2" Generation
Musicals are back, dance classes are filled, clinicians are facing more dancers or former dancers with musculoskeletal problems, and dance medicine experts are urging clinicians to heed the beat of dancing feet...
Thursday Aug 02, 2007
FDA Stops Arthritis Gene Therapy Trial After Patient Dies
CIAOMed takes an in-depth look into what went wrong in the inflammatory arthritis gene therapy trial that resulted in a patient's death and what this incident may mean for the future of gene trials, particularly in arthritis...
Wednesday Jul 25, 2007
Targeted Genetics' Inflammatory Arthritis Phase I/II Trial Placed on Clinical Hold
Targeted Genetics Corp, a clinical-stage biotechnology company, announced that after recent discussions with the US FDA, the phase I/II clinical study of tgAAC94, an investigational therapy for the treatment of inflammatory arthritis, has been placed on clinical hold.
Thursday Jun 21, 2007
Genzyme Files for FDA Approval of Single-Treatment Synvisc-Oneâ„¢ for OA Knee Pain
Genzyme Corp announced filing with the US FDA for product marketing authorization (PMA) of Synvisc-Oneâ„¢, the single treatment combining three doses of Synvisc® (hylan G-F 20) that provides up to 6 months of pain relief from osteoarthritis (OA) of the knee...
Tuesday May 15, 2007
Echorheumatology: Will Growing Interest in Musculoskeletal Ultrasonography Result in a New Subspecialty?
UK rheumatologists sound off on some of the barriers to in-office ultrasonography...
Thursday Apr 26, 2007
Local Gene Therapy for RA Intra-articular Anti-TNF Gene Transduction Reduces Joint Inflammation in RA Animal Model
An anti-TNF gene therapy vector carried by an adeno-associated retrovirus vector and injected into inflamed joints successfully reduced joint inflammation and levels of inflammatory markers in an animal model of RA...
Wednesday Apr 25, 2007
Varus Alignment Doubles Risk for Knee OA in Overweight Subjects
Varus knee alignment precedes and doubles the risk of new-onset knee OA in overweight or obese subjects and worsens disease progression...
Wednesday Mar 21, 2007
BioMimetic Receives Orphan Drug Designation for rhPDGF-BB Treatment of Osteonecrosis of the Jaw
BioMimetic Therapeutics, Inc, an emerging leader in developing and commercializing bioactive drug-device combination drugs to heal musculoskeletal injuries and disease, including periodontal, orthopaedic, spine and sports injuries, announced that it has received orphan drug designation from the US FDA for its protein therapeutic, recombinant human platelet-derived growth factor (rhPDGF-BB)...
Tuesday Jan 23, 2007
Can the Web Help Doctors Get RA Patients Moving? Maybe
RA patients randomized to an individualized, Internet-based exercise program report more physical activity than those given general exercise information, but the electronic monitor does not confirm their reports...
Monday Dec 04, 2006
Genzyme's Synvisc® Demonstrated to Improve Osteoarthritis Knee Pain With Single Dose
Genzyme Corporation announced preliminary results from a study conducted in Europe that indicate that patients treated with a single dose of Synvisc® (hylan G-F 20) achieved a statistically significant improvement in pain from osteoarthritis (OA) of the knee over 26 weeks compared with those using placebo.
Tuesday Nov 07, 2006
Study IDs Predictors of Poor Outcome in Enthesitis-Related Arthritis
Enthesitis-related arthritis (ERA) patients tend to have worse outcomes than children with other subtypes of juvenile idiopathic arthritis (JIA). Predictors of poor outcome include family history of related diseases, the presence of HLA-DRB1*08, the absence of a protective HLA subtype, and persistently elevated erythrocyte sedimentation rate (ESR)…
Thursday Oct 19, 2006
Conventional strength training program has little effect on knee OA progression
Conventional strength training exercises have little effect on progression of knee osteoarthritis... Mikesky AE, et al. Arthritis Care & Research 2006;55:690-693.
Tuesday Oct 03, 2006
Genzyme's Synvisc Receives European Approval to Expand Label to Include the Treatment of OA Pain of the Ankle and Shoulder
Genzyme Corporation announced that it has received European approval to expand the CE mark labeling for SynviscR (hylan G-F 20) to include treatment of pain due to osteoarthritis (OA) of the ankle and shoulder. Genzyme expects to begin marketing Synvisc in the EU with its new label immediately.
Wednesday Aug 30, 2006
Joint Distraction May Delay Need for Joint Replacement in Advanced Osteoarthritis
Temporarily stretching knees or ankles a bit to take the load off cartilage and subchondral bone promotes healing, reduces pain, improves function, and might help some osteoarthritis patients defer or even avoid total joint replacement...
Wednesday Aug 23, 2006
Genzyme Files for European Approval to Expand Label for Synvisc in Ankle and Shoulder Indications
Genzyme Corp. announced that it has filed with the European authority to expand the continuing education mark for Synvisc® (hylan G-F 20) to include treatment of pain due to osteoarthritis (OA) of the ankle and shoulder...
Monday Oct 24, 2005
Studies Outline Weaknesses of DAS28 as Rheumatoid Arthritis Assessment Tool
Two new studies add to a growing body of evidence suggesting that the disease activity score-28 (DAS28), a tool often used to determine the intensity of antirheumatic therapy, is not an appropriate gauge of remission in rheumatoid arthritis (RA).
Tuesday Sep 06, 2005
Aromatase Inhibitors Linked to Arthralgias
With increasing use of aromatase inhibitors as both a breast cancer treatment and preventive agent, rheumatologists should be aware of associated joint pain and musculoskeletal aching... Felson DT, Cummings SR. Arthritis Rheum. 2005;52:2594-2598.
Monday Mar 14, 2005
Hyaluronate Injection Improves Function of Arthritic Ankle
Investigator-initiated pilot study indicates that sodium hyaluronate provides sustained relief of pain and improved function in patients suffering from osteoarthritis of the ankle...72nd Annual Meeting of the American Academy of Orthopaedic Surgeons; February 23-27, 2005; Washington, DC.
Saturday Mar 12, 2005
Genzyme Acquires a Second-Generation Cartilage Repair Product; Buys Back Rights to SynviscR
Genzyme Corp has acquired Verigen AG, a private German company that has developed a proprietary cell-therapy product for cartilage repair.
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