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Found 97 result(s) FROM 1963 pages containing the term 'injury prevention'.
Thursday Apr 22, 2010
Does PRP Therapy Actually Speed Healing?
The controversial blood treatment is gaining popularity amongst athletes, but studies showed mixed results on how effective it is...
Thursday Mar 18, 2010
Knee Replacements May Improve Balance
Joint replacement may improve an elderly patient's balance and prevent falls...
Thursday Feb 11, 2010
Merck Settles Vioxx Lawsuits
Merck & Co. has agreed to settle lawsuits over their withdrawn painkiller Vioxx with a strengthening of safety procedures, change of leadership, and payment of legal fees...
Wednesday Nov 18, 2009
FDA Wants Pain Pump Label Warnings
Chondrolysis follows continuous intra-articular local anesthetic infusion, FDA says...
Friday Oct 16, 2009
EMG Finds “High Risk” Zone for ACL Tears in Female Athletes
Reduced semitendinosus (ST) and elevated vastus lateralis (VL) activity increase the risk of ACL tear—and taking bits from the ST for ACL repair is probably a mistake...
Thursday May 28, 2009
Supreme Court to Hear Vioxx Case
The US Supreme Court will decide whether Merck should be protected from Vioxx shareholder suits...
Wednesday May 13, 2009
Persistent Sore Ankle Might Be Damaged Tendon
Physicians should consider peroneal tendon injury in patients with refractory lateral ankle pain...
Friday Apr 24, 2009
Knee Laxity Tied to Menstrual Cycle
Female athletes are 2 to 8 times more likely to injure their ACL ligaments than men, and 3 new studies say that knee joint laxity related to the menstrual cycle is to blame...
Wednesday Feb 25, 2009
ACL Repairs Becoming More Common in Kids, Don't Shorten NFL Careers
Anterior cruciate ligament (ACL) reconstruction is becoming more common in school-age athletes and needs longer healing time than is sometimes allowed, but it need not jeopardize a professional sports career...
Tuesday Feb 24, 2009
New Program Prevents ACL Tears In High School Girls' Sports
A pilot program to prevent anterior cruciate ligament (ACL) tears among female high school athletes has been so successful that it will be expanded to over 11,000 high school athletes...
Friday Jan 30, 2009
Psoriasis Gene Studies Fill In More Pieces of the Puzzle
New genetics data suggest novel approaches to psoriasis treatment...
Wednesday Dec 03, 2008
Data from KANON Patients Blow Hole in ACL Repair
Surgical reconstruction was not better than training alone for restoring muscle strength and function after ACL injury…
Thursday Nov 06, 2008
Falls Are Leading Cause of Injury to Seniors
The elderly have an increased risk of falls and bone injuries, but certain preventive measures can help protect them…
Thursday Oct 16, 2008
The Scan That Didn’t Scan
Both doctors and patients rely heavily on findings from MRI scans, but the quality of MRI can be erratic and not always reliable…
Wednesday Sep 17, 2008
NSAIDs May Block Prostate Cancer Detection
Regular use of nonsteroidal anti-inflammatory drugs might reduce serum levels of prostate specific antigen (PSA) and interfere with prostate cancer detection...
Monday Sep 15, 2008
Study Rules Against Arthroscopy for Most Knee OA Cases
Arthroscopy is not effective for the treatment of knee osteoarthritis (OA), but an editorialist urges clinicians not to throw out the baby with the bathwater as arthroscopy can—and does—help knee OA patients in whom a coexisting knee problem such as a meniscal tear or a loose piece of cartilage is causing the majority of their symptoms…
Thursday Sep 04, 2008
Omeros Enters Into Agreement With Affitech for Anti-inflammatory Therapeutics, Awaits Phase III Clinical Trial Results for Agent
Omeros Corp and Affitech AS have entered into an agreement for the discovery and development of fully human antibodies for Omeros’ MASP-2, which mediates activation of the complement system via the lectin pathway...
Thursday Sep 04, 2008
Scientists Discover How Osteoarthritis Destroys Cartilage
New discovery may lead to preventive treatment for osteoarthritis…
Tuesday Sep 02, 2008
Naproxcinod Moves Ahead in Pivotal Phase III Study in Osteoarthritis
The next generation of COX inhibitors is likely to include the nitric oxide-donating CINODs, the first of which (naproxcinod) is in phase III trials...
Friday Aug 29, 2008
Ligaments Tie Together OA Pathology
Ligaments are emerging as the key to understanding why osteoarthritis develops in nontraumatized joints...
Thursday Aug 28, 2008
Mesoblast Reports Preclinical Study Shows Allogeneic Stem Cells in Ewes are Safe, Effective for Cervical Spine Fusion; Therapy May Receive Boost From US FDA’s Recent Alert of Life-Threatening Complications Associated With rhBMP in Cervical Spine Fusions
Mesoblast is currently in phase II clinical trials for fusion of the lumbar spine and, based on these new results, will extend its market opportunity to cover the entire spectrum of spinal fusion. Subject to FDA approval, Mesoblast's therapy will eliminate the need for autograft...
Tuesday Aug 19, 2008
Cheerleading More Dangerous Than High-Flying Olympic Gymnastics
Cheerleading routines resemble competitive gymnastics ever more closely but are more dangerous, accounting for two thirds of severe sports injuries to female high school and college students, and consuming 25% of the money that the NCAA insurance program spends on student athletes...
Tuesday Aug 19, 2008
A Quirky Athletic Tape Gets Its Olympic Moment
Kinesio athletic tape has played a prominent role at this summer's Olympic Games in Beijing, with many athletes swearing by its ability to relieve pain and promote healing of injured muscles...
Wednesday Aug 06, 2008
Statins May Help Bone Healing
Statins may improve bone healing, according to new research in an animal model of neurofibromatosis type 1 (NF1)…
Wednesday Jul 30, 2008
Ore Pharmaceuticals Files IND Application With US FDA for GL1001, a Nanomolar Inhibitor of ACE2, to Treat IBD
GL1001, an orally administered small molecule, is the first clinical-stage inhibitor of the ACE-related carboxypeptidase (ACE2), a membrane-associated and secreted enzyme expressed predominantly on endothelium...
Monday Jun 30, 2008
Preclinical Studies Show that IGF-1-Producing Adult Stem Cells Zoom to Fracture Site, Speed Healing
Preclinical data reported at the 2008 ENDO meeting show that adult stem cell injections might be one approach to treating nonhealing osteoporotic fractures...
Wednesday Jun 25, 2008
Exercise Helps Prevent Knee OA in the Young and the Young at Heart
Moderate exercise may help prevent knee osteoarthritis (OA) in young and middle-aged individuals…
Tuesday Jun 10, 2008
Novartis’ Once-Yearly Reclast® Injection 5 mg Receives Revised US Label; Indication to Include Prevention of Fractures After a Hip Fracture
The FDA has broadened the indication for once-yearly Reclast® (zoledronic acid) for postmenopausal osteoporosis to include the prevention of new clinical fractures in patients who have recently had a low-trauma hip fracture...
Tuesday Apr 29, 2008
Women Risk Bone Loss After Knee Surgery
Women who underwent surgery to repair a torn ACL suffered significant bone loss surrounding the knee…
Friday Apr 18, 2008
Novartis Announces Once-Yearly Reclast Better Than Risedronate at Increasing BMD in GIO Patients; US FDA Approval Sought for Treatment and Prevention of GIO
Novartis Pharmaceuticals Corp reported that a once-yearly infusion of Reclast® (zoledronic acid) injection 5 mg was significantly better than risedronate at increasing BMD in patients with glucocorticoid-induced osteoporosis...
Thursday Apr 17, 2008
Splints as Good as Plaster Casts for Minor Fractures
Removable splits are a safe, effective, and cheaper option than traditional plaster casts for minor wrist fractures in children, but are easily tampered with…
Monday Apr 14, 2008
Twin Spine Study Shows Genes, Not Injuries Cause Most Disc Problems
Researchers with the Twin Spine Study show that most degenerative back problems are linked to genes, not to aging, injuries, lifting, or driving. They also identified several genes involved...
Tuesday Mar 18, 2008
Genzyme Reports That US Data From Large Outcome Studies of Carticel® Support Long-Term Clinical Duration; Prior Marrow Stimulation Techniques May Compromise Treatment With Carticel
Genzyme announced that almost 90% of patients treated with Carticel who experienced improvement in knee function at an early follow-up, sustained their improvement for almost 10 years...
Tuesday Mar 18, 2008
'Boot Camps' Treat Pain Sufferers
An intensive 4-week program works to alleviate chronic pain through biological, psychological, and social approaches…
Friday Mar 07, 2008
ACL Tears Should Be Repaired Within 12 Weeks of Injury
ACL reconstruction should be done within 12 weeks of injury to avoid irreparable meniscus damage...
Friday Mar 07, 2008
Sports Doctors Urge for More Injury Prevention in Women Athletes
Sex matters in sports injuries, and more attention to special problems of women athletes is needed...
Tuesday Feb 19, 2008
Big-Time Injury Strikes Little Players
An increasing number of child and adolescent athletes are being diagnosed with torn ACLs...
Thursday Feb 14, 2008
Nearly All Back Pain Improves By 5 Years
A follow-up study of low back pain finds that >90% of patients report significant improvement within 5 years...
Thursday Feb 14, 2008
Risedronate for Prevention of Bone Mineral Density Loss in Patients Receiving High-Dose Glucocorticoids
Risedronate improves spinal bone mineral density in patients receiving high-dose glucocorticoids...
Tuesday Feb 05, 2008
MGH Center is a Pioneer in Knee Repair
Physicians at the Massachusetts General Hospital sports medicine center are experimenting with new techniques for joint reconstruction in athletes...
Monday Feb 04, 2008
Cochrane Review: Alendronate Safe, Effective for Secondary Fracture Prevention
Alendronate can stave off vertebral, nonvertebral, hip, and wrist fractures among postmenopausal women with low bone density and/or those with previous fractures...
Thursday Jan 31, 2008
Single Face-to-Face Patient Ed Session Helps Acute, But Not Chronic, Back Pain Patients Return to Work Sooner
A single 2.5 hour individual patient education session given by a trained healthcare specialist can hasten the return to work for patients with acute or subacute low back pain (LBP), but does not have a similar effect on chronic LBP...
Friday Jan 18, 2008
Third Study Finds No Gain to Bracing Knee After ACL Reconstruction
Functional knee braces are widely used for patients returning to sports or other activity following ACL reconstruction, but a randomized, controlled trial found that the costly braces are no better than neoprene sleeves—and probably no better than not bracing at all...
Thursday Jan 17, 2008
Elan, Biogen Idec Gain US FDA Approval of Tysabri® for Treatment of Moderate-to-Severe Crohn's Disease
Elan Corp, plc and Biogen Idec announced the approval of a supplemental Biologics License Application for Tysabri® (natalizumab) for inducing and maintaining clinical response and remission in adult patients with active moderate-to-severe Crohn's disease...
Monday Dec 17, 2007
Pain in Knees with Meniscal Damage is Due to OA
Knee pain in middle-aged and older adults who have meniscal damage is due to the osteoarthritis (OA) that often develops in such knees, not to pain from the torn meniscus...
Tuesday Nov 20, 2007
Novartis Says Health Regulators in UK and Germany Suspend Marketing and Sale of Prexige® Pending Outcome of European Regulatory Review
Novartis Pharmaceuticals AG announced that health regulators in the UK and Germany have suspended the marketing and sale of Prexige® (lumiracoxib), a COX-2 inhibitor for patients with osteoarthritic pain, following a review of the drug's benefit/risk profile...
Friday Nov 09, 2007
Breaking News: Merck Tosses in Towel on Vioxx Settlements
After years of promising to fight each individual lawsuit brought by former users of Vioxx, Merck has agreed to settle 27,000 cases...
Monday Oct 01, 2007
Vigorous Exercise May Benefit Knees
Breaking a sweat while exercising at least once a week for around 20 minutes may stave off the development of knee osteoarthritis...
Wednesday Sep 26, 2007
Sucampo Pharmaceuticals Begins Phase II, Dose-Finding Trial of Cobiprostone, a Chloride-Channel Activator, for the Prevention of NSAID-Induced Ulcers in Arthritis Patients
Sucampo Pharmaceuticals, Inc, announced that it has enrolled the first patient in a multicenter, phase II, dose-finding trial evaluating the prostone cobiprostone (SPI-8811) for the prevention of ulcers and other gastrointestinal injuries in arthritis patients treated with nonsteroidal anti-inflammatory drugs (NSAIDs)...
Wednesday Sep 19, 2007
Anticytokine Shots May Aid Healing Following Knee Injuries
Shooting TNF inhibitors or IL-1 blockers directly into the joint may help promote healing following meniscal tears…McNulty AL, et al. Arthritis Rheum. 2007;56:doi:10.1002/art [Epub ahead of print].
Tuesday Sep 11, 2007
Synovio-Entheseal Complex Seen As Key to Psoriatic Arthritis, Spondylarthropathies
The synovio-entheseal complex (SEC), where the enthesis and synovium come together in a synovial joint, links joint damage and innate immune activation leading to joint inflammation...McGonagle D, et al. Arthritis Rheum. 2007;56:2482-2491.
Monday Sep 10, 2007
Jury Out on Whether Surgical Repair of ACL Tears Staves Off OA
Little convincing evidence supports surgical repair of the anterior cruciate ligament or meniscus as a way of preventing OA, but the problem may lie in the way the studies have been done, not in the surgery…Lohmander LS, et al. Am J Sports Med. 2007 Aug 29; doi: 10.1177/0363546507307396 [Epub ahead of print].
Tuesday Aug 28, 2007
New Zealand Regulatory Authority, Medsafe, Revokes Consents for Prexige® 200 mg and 400 mg Tablets; Novartis Issues Recall Notice
The Medicines and Medical Devices Safety Authority, Medsafe, has revoked the consents allowing the supply in New Zealand of the COX-2 anti-inflammatory medicine Prexige (lumiracoxib) 200 mg and 400 mg tablets on the grounds that the tablets can no longer be administered or used safely for the purposes indicated in the regulatory application for consent...
Monday Aug 27, 2007
Harkness Dance Medicine Head Urges Clinicians to Prepare for the "High School Musical 2" Generation
Musicals are back, dance classes are filled, clinicians are facing more dancers or former dancers with musculoskeletal problems, and dance medicine experts are urging clinicians to heed the beat of dancing feet...
Tuesday Aug 14, 2007
Novartis Withdraws Lumiracoxib (Prexige®) in Australia in Response to Decision From Therapeutic Goods Administration to Cancel Registration
Novartis Pharmaceuticals Australia Pty Ltd announced the immediate recall of all doses (100 mg, 200 mg, and 400 mg tablets) of lumiracoxib (Prexige®), a COX-2 inhibitor for the treatment of osteoarthritis (OA) and acute pain...
Monday Jul 23, 2007
Is "Tech Neck" the Latest Casualty From Excessive Blackberry Use?
Rheumatologists and orthopaedists may be seeing an influx of patients complaining of neck pain caused by tilting their heads to use cell phones, BlackBerry devices, iPods, or handheld games.
Wednesday Jul 18, 2007
Brain Function Linked to "Noncontact" Knee Injuries
Differences in brain function may predispose athletes to ACL injury…Swanik CB, et al. Am J Sports Med. 2007;35:943-948.
Thursday Jul 05, 2007
Too Much Early, Aggressive Care Slows Recovery From Whiplash
Early, aggressive treatment of whiplash impedes recovery, and adding chiropractic to general medical care slows recuperation even more...
Thursday Jun 28, 2007
FDA Approves New Labeling for Carticel® in Repair of Articular Knee Cartilage
Genzyme Corporation announced that the US FDA has approved new labeling for Carticel® based on the company's completing a final FDA postapproval commitment study...
Tuesday May 08, 2007
2-Year Results Support Use of New Chondrocyte Graft to Repair Knee OA Damage
Two-year follow-up of a new 3-dimensional scaffold that permits grafting of autologous chondrocyte to repair knee cartilage defects show promising results in both knee OA and knee trauma, and the procedure can be done arthroscopically...
Friday Apr 27, 2007
Wyeth Receives Approvable Letter from FDA for Bazedoxifene for the Prevention of Postmenopausal Osteoporosis
Wyeth Pharmaceuticals, a division of Wyeth, announced that the US FDA has issued an approvable letter for bazedoxifene (ViviantTM), a selective estrogen receptor modulator (SERM) for the prevention of postmenopausal osteoporosis...
Thursday Mar 01, 2007
Calcium-Containing Crystals May Contribute to OA Joint Destruction, Be Amenable to Treatment
Evidence is accumulating that calcium-containing crystals, which are common in OA synovial fluids in some patients, contribute to the development of rapidly destructive arthritis and might be a target for therapeutic intervention...
Monday Feb 26, 2007
Lupus Patients Clear UV-Damaged "Sunburn Cells" but May Have Unusual Inflammatory Reaction to Them
Sunlight can trigger new skin lesions and worsen disease activity in lupus; this might reflect an abnormal inflammatory response to UV-damaged cells, despite the ability to clear them normally from the epidermis...
Thursday Feb 15, 2007
Experts at the 74th Annual Meeting of the American Academy of Orthopaedic Surgeons Predict Clinically Useful Gene Therapy, Tissue Engineering Will Be Available "in 5 to 10 Years"
Presentations at the AAOS meeting include advances in both gene therapy and tissue-engineered products for cartilage, bone, and tendon repair...
Wednesday Jan 31, 2007
First, Do No Harm—Exercise Won't Up Risk of Knee OA
Exercise neither protects against nor increases the risk of knee osteoarthritis (OA) in older, overweight adults…
Tuesday Jan 30, 2007
Whiplash Rarely Results in Widespread Pain
New research shows that individuals with whiplash who report early symptoms of depression and those with severe neck injury are most at risk for widespread pain...
Friday Dec 22, 2006
New Studies Suggest That Autoantibodies Damage Brain, Cause Cognitive Impairment in SLE Patients
The cognition and mood disturbances common in lupus patients might be due in part to autoantibodies that target the NMDA receptor and cause progressive damage of the amygdala and hippocampus...
Tuesday Nov 21, 2006
Study Helps Explain Why Smoking Slows Ligament and Bone Healing
Smoking cigarettes delays cartilage formation in healing bone fractures and slows type I collagen production and recruitment of cells linked to healing of torn ligaments…
Thursday Sep 14, 2006
Anthera Licenses Portfolio of Anti-Inflammatory Products from Lilly and Shionogi; Raises $36 Million in Venture Financing
Anthera Pharmaceuticals, a privately-held biopharmaceutical company developing drugs for the treatment of inflammatory diseases, announced that it has entered into a license agreement with Eli Lilly and Company and Shionogi & Co., Ltd., under which Anthera has obtained worldwide (except for Japan) development and commercialization rights to an entire platform of clinical and preclinical inhibitors of phospholipase A2 (PLA2) developed by Lilly and Shionogi as part of their collaboration.
Monday Sep 11, 2006
Small, Portable In-Office MRI Can Monitor Response to Therapy in RA
As RA treatments become more effective and expensive, monitoring response to therapy becomes more important. Two new studies suggest that small, portable MRI devices might help...
Wednesday Aug 16, 2006
Biogen Idec and University of Adelaide Find TWEAK Is a Novel Arthritogenic Mediator; Potential New Pathway in Rheumatoid Arthritis and Osteoarthritis Disease Process
Biogen Idec announced studies published in the August 15, 2006, issue of the providing evidence that TWEAK (TNF-like weak inducer of apoptosis), a TNF family member, is a novel arthritogenic mediator that contributes to joint tissue inflammation, angiogenesis, and destruction, and may inhibit endogenous repair.
Thursday Aug 10, 2006
Michigan Researchers to Study ACL Injuries, Bone Bruises, in Knee OA
Anterior cruciate ligament (ACL) injuries are common in young athletes and often lead to later knee osteoarthritis (OA). A new prospective study will try to determine whether bone bruises add to that risk.
Wednesday Aug 09, 2006
Low Estrogen Levels Increase Risk of Knee OA in Women
Low concentrations of estradiol and urinary 2-hydroxyestrone may increase the risk of developing knee osteoarthritis among women approaching menopause... Sowers MFR, et al. Arthritis Rheum. 2006;54:2481-2487.
Thursday Jul 20, 2006
Bioengineered Cartilage Successfully Transplanted in Osteoarthritic Knees
Cells taken from areas of healthy cartilage can be grown on hyaluronic acid scaffolds and used to patch damaged knees, even joints that have already progressed to osteoarthritis....Hollander AP, et al. Tissue Engineering 2006;12:1-12.
Wednesday Jun 14, 2006
MRI Reveals Little in Low Back Pain
Routine use of MRI in early episodes of low back pain is probably a mistake... Carragee E. Presented at: American Pain Society 25th Annual Meeting; May 3–6, 2006; San Antonio, Tex.
Thursday May 25, 2006
Hyperosmolar Dextrose Sweetens Chronic Tendinosis
Ultrasound-guided hyperosmolar dextrose injections into tendon relieve chronic tendinosis... Maxwell NJ, Ryan M, Taunton JE, Wong A. Presented at: American Roentgen Ray Society 106th Annual Meeting; April 30–May 5; Vancouver, BC. Abstract 172.
Monday May 08, 2006
Additional Neuropathies Linked to TNF Inhibitors
Guillain-Barré syndrome, demyelinating and axonal neuropathies, and a central nervous system syndrome have been reported recently in patients treated with TNF inhibitors... Shin I-SJ, et al. Arthritis Rheum. 2006;54:1429-1434; Jarand J, et al. J Rheumatol. 2006;33:1018-1020.
Friday Apr 28, 2006
Leukocytes Extend Damage, Kill "Bystander" Chondrocytes in Areas Around Injured Cartilage
Damage to cartilage also kills chondrocytes far from the site of injury, and this distant damage is mediated by inflammatory leukocytes that adhere to ICAM-1 expressed by stressed but otherwise viable chondrocytes. Preventing the early flood of leukocytes into the injured joint or blocking leukocyte attachment to ICAM-1 might reduce long-term damage... Green DM, et al. Arthritis Rheum. 2006;54:1509-1517.
Friday Apr 28, 2006
Brief Pulse of Ultraviolet-A Light Provides Site-Specific Gene Therapy for Damaged Articular Cartilage
A brief pulse of ultraviolet-A light may currently be the safest way to provide site-specific gene therapy for damaged articular cartilage... Maloney MD, et al. J Bone Joint Surg. 2006;88:753-761.
Friday Apr 14, 2006
Testing for Second-Generation Anti-CCP Antibodies in Patients With Early RA is Useful for Predicting Radiographic and Functional Outcomes
Anti-CCP antibodies are a useful diagnostic tool, particularly among seronegative rheumatoid arthritis (RA) patients. The presence of anti-CCP antibodies confers prognostic utility for radiographic and functional outcomes... Quinn MA, et al. Rheumatology. 2005;45:478-480.
Tuesday Mar 14, 2006
Study Associates Meniscal Damage With Advanced Cartilage Loss in Early OA
Meniscal tears and malposition result in cartilage loss in patients with symptomatic knee osteoarthritis... Hunter DJ, et al. Arthritis Rheum. 2006;54:795-801.
Monday Feb 13, 2006
BioMimetic Therapeutics Files for IPO
BioMimetic Therapeutics, Inc, of Franklin, Tennessee, announced that it has filed a registration statement with the US Securities and Exchange Commission...
Wednesday Dec 14, 2005
Critical Therapeutics' Fully Human Monoclonal Antibodies Against HMGB1 Demonstrate Efficacy in Preclinical Models of Inflammation; Triggers $1.25 Million Milestone Payment From MedImmune
Critical Therapeutics, Inc, of Lexington, Massachusetts, announced that its fully human monoclonal antibodies against high mobility group box 1 (HMGB1) provide significant protection...
Friday Nov 04, 2005
Study Provides Additional Clues to the Causes of Systemic Sclerosis and the Potential Efficacy of Paclitaxel
New research in a murine model points to the ability of low-dose paclitaxel (Taxol®) to modulate transforming growth factor-beta (TGF-ß) and lessen fibrosis in systemic sclerosis patients, findings that also provide additional clues to the pathogenesis of the disease... Liu X, et al. PloS Med. 2005;2:e354
Monday Sep 19, 2005
A Leading Rheumatologist Reflects on How Cyclooxygenase Became a Household Word
Just as it appeared that the dust from the great COX-2 controversies had begun to settle, a jury in Texas awarded a plaintiff a judgment against Merck & Co for one quarter of a billion dollars - indeed, for a death that, arguably, was not Vioxx-related.
Monday Aug 15, 2005
Actonel with Calcium Approved by US FDA for the Prevention and Treatment of Postmenopausal Osteoporosis
The Alliance for Better Health, formed by Procter & Gamble Pharmaceuticals and Aventis Pharmaceuticals (now a member of the Sanofi-Aventis Group), has announced...
Monday Aug 08, 2005
Velcura Receives $1.3 Million SBIR Grant for New Osteoporosis Drugs
Velcura Therapeutics®, Inc, a biotechnology company focused on developing drugs for bone diseases, received a $1.3 million Phase II Small Business Innovation Research (SBIR) grant from the National Institute on Aging, of the National Institutes of Health, to use proteomics-based drug discovery in human osteoblasts to identify bone disease biomarkers and targets, and develop new drugs that stimulate bone formation.
Monday Jul 25, 2005
Government Crackdown on Palladone and Fentanyl Continues to Fuel Fear of Prescribing Pain Medication
Withdrawal of Palladone in the US, the advisory report issued on the fentanyl patch, and the continued DEA scrutiny of doctors who prescribe opioids and other narcotic analgesics may have a chilling effect on the optimal use of these agents for the relief of acute and persistent pain.
Wednesday Jun 22, 2005
Phytomedics In-Licenses Anti-Inflammatory Sesquiterpene Lactones
Phytomedics Inc, a Dayton, New Jersey-based developer of novel botanical therapeutics, announced that it has acquired exclusive US licensing rights from Louisiana State University in Baton Rouge for an invention pertaining to sesquiterpene (terpene compounds with 15 carbon atoms) lactones (a cyclic ester) and sesquiterpene lactone-containing plant extracts for the treatment of severe inflammatory disorders such as psoriasis, pemphigus vulgaris, sepsis, and postreperfusion injury.
Wednesday Mar 30, 2005
FDA Approves Monthly Ibandronate for Treatment and Prevention of Osteoporosis
The new formulation simplifies osteoporosis drug therapy and addresses problems of adherence among patients using bisphosphonates
Monday Feb 07, 2005
"Blackberry Thumb" Emerging as Common Ergonomic Complaint
Reports suggest that rheumatologists may see an increase in cases of de Quervain's tenosynovitis as a result of overzealous blackberry use...
Wednesday Dec 22, 2004
National Institutes of Health Halts Alzheimer's Prevention Trial Involving Aleve and Celebrex
Federal officials noted that patients taking the OTC formulation of naproxen had a 50% greater rate of cardiovascular (CV) events compared with placebo; those in the COX-2 inhibitor arm of the trial saw no increased CV risk...National Institutes of Health, December 20, 2004.
Tuesday Dec 21, 2004
Cancer-Prevention Trial Reveals Elevated Cardiovascular Risk Associated With Celebrex
National Cancer Institute study results, which showed a heightened cardiovascular risk versus placebo among patients taking the COX-2 inhibitor celecoxib at up to 4 times higher than recommended doses, runs counter to recent evidence that the agent may have cardioprotective properties in some arthritis patients... Kimmel SE, et al. Ann Intern Med. 2005;142(3).
Monday Nov 15, 2004
EPIC Study: Alendronate's Benefits for Osteoporosis Prevention Continue Up to 6 Years
Therapy with the bisphosphonate is effective long-term in preserving bone mineral density in postmenopausal women, and should serve as a promising strategy for the prevention of osteoporosis in the post-HRT era& McClung MR, et al. J Clin Endocrinol Metab. 2004;89:4879-4885.
Thursday Oct 21, 2004
State-of-the-Art Lectures Reflect Pioneering Research in Rheumatology in the Past Year
The speakers highlighted new research in basic science, including genetic mechanisms at work in RA, and in clinical studies that further understanding of the efficacy of various therapeutic strategies…Barton A, et al. Arthritis Rheum. 2004.;50:1117-1121; Edwards JC, et al. N Engl J Med. 2004;350:2572-2581.
Monday Oct 18, 2004
Identical Twins Have 5 Times the Risk of Joint Replacement Surgery If Their Twin Has the Procedure
Swedish researchers discover a genetic link for osteoarthritis risk, especially among identical twins, adding to previous findings that did not distinguish between heredity and shared family environment... Lohmander S, Johnell O, Pedersen NL. Poster presented at: Annual Meeting of the American College of Rheumatology; October 18, 2004; San Antonio, Texas . . Abstract 228.
Tuesday Aug 31, 2004
Primary Care Physician Survey Shows Back Pain Highly Prevalent, Often Involves Spasm
Acute back injuries often have a spasmodic as well as an inflammatory component; treating both expedites recovery.
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