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Found 27 result(s) FROM 1963 pages containing the term 'hippocampal function'.
Thursday Sep 24, 2009
Rituximab Improves SSc Lung Function
A small pilot study has established proof-of-principle that rituximab improves lung function in scleroderma...
Wednesday Aug 26, 2009
Virtual Reality: Fibromyalgia Affects Spatial Navigation
Virtual reality (VR) testing confirms what many fibromyalgia patients suspect: spatial learning deficits related to hippocampal dysfunction...
Tuesday Jul 29, 2008
CEL-SCI Announces Positive Preclinical Results Using CEL-2000, a Chimeric Peptide with Bi-Functional Properties, as RA Vaccine
CEL-SCI Corp announced the discovery of CEL-2000, a novel peptide vaccine for the treatment of RA. Tests showed that CEL-2000 is equivalent or possibly superior to Enbrel® in slowing disease progression and lessening symptoms in mice...
Monday Jun 30, 2008
Ghrelin, Leptin Changes Link Menstrual Dysfunction, Bone Health in Teen Athletes
Changes in two hormones that affect both appetite and estrogen secretion appear to be the link between athletic activity, loss of menstrual function, and bone health in some adolescent female athletes...
Tuesday Jun 17, 2008
At 1 Year, Balloon Kyphoplasty Provides Better Pain, Function Outcomes Than Nonsurgical Care for Osteoporotic Vertebral Fractures
After 12 months, patients with acute vertebral compression fractures treated with balloon kyphoplasty had sustained improvements in pain and function compared with those who received nonsurgical care...
Friday Jun 13, 2008
Clinical, X-ray, and Functional Remission Possible in Early RA With MTX-ETN Combo
Etanercept (ETN) in combination with methotrexate (MTX) was superior to MTX alone in allowing RA patients to achieve clinical remission, radiographic nonprogression, and normalized function...
Wednesday May 14, 2008
Roche’s Fifth Phase III Study for Actemra® Inhibits Joint Damage and Improves Physical Function of Patients With RA
Roche's Actemra® (tocilizumab), a humanized interleukin-6 receptor-inhibiting monoclonal antibody, can significantly inhibit structural damage to joints in patients with RA...
Thursday Apr 10, 2008
Raloxifene Safe for Women With Decreased Kidney Function
The osteoporosis drug raloxifene is safe for women with CKD, effectively promotes bone density, and reduces fractures…
Wednesday Nov 14, 2007
Fish Oil May Improve Symptoms and Endothelial Function in SLE
Omega-3 fish oil may reduce lupus disease activity and improve endothelial function...
Thursday Nov 08, 2007
Centocor, Schering-Plough's Anti-TNF Golimumab Significantly Reduced Signs and Symptoms of AS in Phase III Study; Monthly Treatment Yielded Marked Improvements in Physical Function
Centocor, Inc, a wholly owned subsidiary of Johnson & Johnson, announced that more than half of patients receiving monthly subcutaneous injections of golimumab 50 mg and 100 mg experienced significant and sustained improvements in the signs and symptoms of active ankylosing spondylitis (AS), according to the phase III study (GO-RAISE trial) results...
Wednesday Sep 19, 2007
Falls Increase as Shrinking Kidney Function Lowers Balance, Muscle Strength in Elderly
Creatinine clearance of less than 65 mL/min is associated with an increased risk for falls, apparently because decreasing calcitriol serum levels jeopardizes balance and muscle strength...Dukas LC, et al. ASBMR 2007.
Thursday Aug 02, 2007
TNF Inhibitors May Restore Adrenal Function in RA
TNF inhibitors appear to improve adrenal function in some RA patients, resulting in restoration of stable hormonal homeostasis...
Wednesday Jul 18, 2007
Brain Function Linked to "Noncontact" Knee Injuries
Differences in brain function may predispose athletes to ACL injury…Swanik CB, et al. Am J Sports Med. 2007;35:943-948.
Thursday Feb 01, 2007
Brain Dysfunction Precedes the Development of Fibromyalgia
Abnormalities in the hypothalamic-pituitary-adrenal (HPA) axis can be detected more than a year before the development of fibromyalgia symptoms in patients who are psychologically "at risk." HPA dysfunction appears to increase the chance that psychological stress will trigger chronic widespread musculoskeletal pain...
Friday Dec 22, 2006
New Studies Suggest That Autoantibodies Damage Brain, Cause Cognitive Impairment in SLE Patients
The cognition and mood disturbances common in lupus patients might be due in part to autoantibodies that target the NMDA receptor and cause progressive damage of the amygdala and hippocampus...
Tuesday Nov 14, 2006
Successful Anti-TNF Treatment Restores Regulatory T-Cell Function in RA
TNF inhibitor treatment can restore some of the lost T regulatory (suppressor) cell functioning in patients with RA, which might contribute to suppression of disease flares... Valencia X, et al. Presented at: ACR 2006 Meeting.
Thursday Oct 26, 2006
New Study Casts Doubt on Metabolic Dysfunction in Chronic Fatigue Syndrome
A new study comparing response to exercise in patients with chronic fatigue syndrome (CFS) and fibromyalgia (FM) finds exercise more difficult in CFS/FM patients than in those with CFS alone, but casts doubt on metabolic explanations for CFS…Cook DB, et al. Arthritis Rheum. 2006;54:3351–3362.
Friday Jun 30, 2006
Consider Disease Duration in Comparing Functional Outcomes of RA Treatment
Measures of physical function such as the HAQ become less responsive to treatment effects with increasing duration of RA, so disease duration should be considered in comparing functional outcomes of different treatments...Aletaha D. 2006 EULAR Meeting.
Tuesday Jun 27, 2006
Bosentan Prevents Digital Ulcers, Improves Heart Function in Systemic Sclerosis
Bosentan reduces digital ulcer risk and improves heart function in systemic sclerosis patients... Allanore Y, et al. Presented at: EULAR 2006 Meeting; June 21–34, 2006; Amsterdam, The Netherlands. Abstract OP0120.
Friday Apr 14, 2006
Testing for Second-Generation Anti-CCP Antibodies in Patients With Early RA is Useful for Predicting Radiographic and Functional Outcomes
Anti-CCP antibodies are a useful diagnostic tool, particularly among seronegative rheumatoid arthritis (RA) patients. The presence of anti-CCP antibodies confers prognostic utility for radiographic and functional outcomes... Quinn MA, et al. Rheumatology. 2005;45:478-480.
Thursday Jan 12, 2006
Three Months of Bosentan Therapy Improves Function in SSc-PAH Patients
Three Months of Bosentan Therapy Improves Function in SSc-PAH Patients
Friday Aug 19, 2005
Stem-Cell Transplantation Temporarily Improves Function and Health Status in RA Patients
New research helps delineate some of the benefits and potential limitations of high-dose chemotherapy followed by autologous hematopoietic stem-cell transplantation in patients with severe refractory rheumatoid arthritis. Teng YK, et al. Arthritis Rheum. 2005;52:2272-2276.
Wednesday Aug 10, 2005
Abatacept Reduces Disease Activity and Improves Function in RA Patients Who Failed MTX
Results of a 12-month study show that the first in a class of agents designed to block a costimulatory pathway required for optimum activation of T cells may play an important role in the treatment of rheumatoid arthritis (RA), particularly among patients unresponsive to methotrexate (MTX)... Kremer JM, et al. Arthritis Rheum. 2005;52:2263-2271.
Thursday Jul 28, 2005
Parkinson's Drug Shows Initial Promise in Fibromyalgia
Fibromyalgia patients taking pramipexole, a dopamine3-receptor agonist, reported decreased pain and fatigue and improved function and global status compared with study participants taking placebo... Holman AJ, Myers RR. Arthritis Rheum. 2005;52:2495-2505.
Wednesday Jun 15, 2005
Etanercept Expands PsA Indication to Include Improvement of Physical Function
Amgen Inc and Wyeth Pharmaceuticals announced that the US Food and Drug Administration (FDA) expanded the marketing approval of Enbrel® (etanercept) to include the improvement of physical function in patients with psoriatic arthritis (PsA).
Wednesday Mar 30, 2005
Cognitive-Behavioral Program Helps OA Patients Feel and Function Better
A self-management program that teaches goal setting, self-relaxation, and other behavioral measures improves pain and self-reported function in Dutch cohort... Heuts PH, et al. J Rheumatol 2005;32:543-549.
Monday Mar 14, 2005
Hyaluronate Injection Improves Function of Arthritic Ankle
Investigator-initiated pilot study indicates that sodium hyaluronate provides sustained relief of pain and improved function in patients suffering from osteoarthritis of the ankle...72nd Annual Meeting of the American Academy of Orthopaedic Surgeons; February 23-27, 2005; Washington, DC.
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