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Found 112 result(s) FROM 1963 pages containing the term 'exercise'.
Wednesday Mar 31, 2010
Fibromyalgia Symptoms May be Alleviated by Short Bursts of Physical Activity
Lifestyle physical activity intervention may reduce fibromyalgia symptoms and improve physical function...
Wednesday Nov 11, 2009
Cooling RA Skin May Slightly Shift Doppler US
Cooling (but not warming) the skin has a modest effect on ultrasound Doppler measurements in RA...
Friday Oct 16, 2009
EMG Finds “High Risk” Zone for ACL Tears in Female Athletes
Reduced semitendinosus (ST) and elevated vastus lateralis (VL) activity increase the risk of ACL tear—and taking bits from the ST for ACL repair is probably a mistake...
Tuesday Sep 29, 2009
Fibromyalgia Goes Legit
Better understanding of the brain chemistry anomalies in fibromyalgia have paved the way toward more effective treatments for this pain disorder...
Wednesday Sep 09, 2009
RA Joints Protected by More Fat, Less Adiponectin
Adiponectin is the link between fatness and lower joint damage in RA...
Wednesday Aug 05, 2009
Psoriasis: Not Just Skin Deep
Mark G. Lebwohl, MD says psoriasis affects the heart and other vital organs, and treatment with TNF-blockers may reduce the risk of these comorbidities...
Thursday Jul 16, 2009
Tubular Diskectomy Patients Don't Recover Faster
Recovery from minimally invasive tubular diskectomy for sciatica is no quicker than from conventional microdiskectomy...
Tuesday Jul 07, 2009
Quercetin Boosts Exercise Capacity
New research shows that quercetin supplementation boosts endurance and maximal oxygen capacity in healthy, active but untrained men and women...
Monday Jun 08, 2009
Tai Chi Prevents Disability in Chronic Musculoskeletal Pain
The ancient Chinese exercise practice of Tai Chi may decrease pain, prevent disability, and improve overall physical health and quality of life for people with chronic musculoskeletal pain...
Thursday May 21, 2009
Massage Does Not Up Blood Flow After Exercise
Massage may be beneficial after exercise, but not because it improves circulation and removes lactic acid and other waste products from the muscles...
Friday Apr 24, 2009
Knee Laxity Tied to Menstrual Cycle
Female athletes are 2 to 8 times more likely to injure their ACL ligaments than men, and 3 new studies say that knee joint laxity related to the menstrual cycle is to blame...
Thursday Apr 23, 2009
Merck Inks Deal with Galapagos in Inflammatory Diseases
Merck and Galapagos have signed a multi-year agreement for discovery and development of new drugs for inflammatory disease...
Wednesday Apr 22, 2009
After 80, Weightlifting Does Not Grow Muscles
Three months of weight lifting did not increase muscle mass in octogenarian women, although they were able to lift more weight...
Monday Apr 13, 2009
Caffeine May Be New Rx for Pain-Free Exercise
Jumpstarting a workout with a jolt of java or another readily available caffeinated beverage may reduce the pain associated with exercise...
Thursday Apr 02, 2009
Back Pain: Too Little Exercise, Too Much Imaging
Patients with low back pain are using too many ineffective treatments and too few of those proven effective...
Tuesday Feb 24, 2009
New Program Prevents ACL Tears In High School Girls' Sports
A pilot program to prevent anterior cruciate ligament (ACL) tears among female high school athletes has been so successful that it will be expanded to over 11,000 high school athletes...
Tuesday Feb 17, 2009
Exercise Rx’s for Neck, Back Pain Underused
Less than 50% of chronic back and neck pain patients receive exercise prescriptions despite the proven effectiveness of exercise in treating such pain...
Thursday Feb 12, 2009
Strength Training Bests Conventional Rehab After Knee Replacement
A progressive quadriceps strengthening program may help total knee arthroplasty patients approach the functional level seen among healthy peers...
Thursday Feb 05, 2009
Low Back Pain Seldom Needs Surgery
Patients with discogenic low back pain can be advised to get out of bed, get some exercise, and assume that they will not need surgery...
Monday Feb 02, 2009
Rituximab B-Cell Depletion Stops JIA
Systemic onset JIA responded dramatically to B-cell depletion with rituximab...
Thursday Jan 15, 2009
Parkinson's Disease Puts Bones, Joints at Risk
The symptoms of Parkinson’s disease—tremors, rigidity in the joints, and balance problems—can lead to reduced bone mass and a greater risk of falls, resulting in heightened numbers of bone fractures and joint injuries…
Tuesday Jan 06, 2009
Forget Knee OA Glucosamine, Orthotics—Lose Weight, AAOS Says
New knee arthritis guidelines from the premier American orthopaedics society say that glucosamine and/or chondroitin, custom-made shoe foot orthotics, and needle lavage are basically useless for the treatment of knee OA, but losing weight helps...
Wednesday Dec 03, 2008
Data from KANON Patients Blow Hole in ACL Repair
Surgical reconstruction was not better than training alone for restoring muscle strength and function after ACL injury…
Thursday Nov 06, 2008
Falls Are Leading Cause of Injury to Seniors
The elderly have an increased risk of falls and bone injuries, but certain preventive measures can help protect them…
Monday Oct 27, 2008
Tai Chi Rx for Knee OA
Tai chi may help treat pain and physical impairment among patients with severe knee osteoarthritis…
Thursday Oct 23, 2008
Pain Experts Clear Strength Training for Fibromyalgia
Strength training should have a role in the care and treatment of patients with fibromyalgia…
Thursday Oct 09, 2008
Fat Limbs Linked to Disability in Arthritis
Rheumatoid arthritis patients with more fat on their arms and legs suffer a greater degree of disability from their disease than those with thinner limbs…
Friday Oct 03, 2008
Occupational Therapy May Help OA Patients Get Moving
Occupational therapy may help get patients with knee and hip osteoarthritis (OA) lead more active lives…
Thursday Sep 25, 2008
Disease Factors, Corticosteroids Nearly Double Heart Attack Risk in RA Patients
RA-specific factors and corticosteroid use significantly increase the risk of myocardial infarction in RA patients…
Thursday Sep 25, 2008
Bone Loss Stable on Restricted Calorie Diet
Overweight adults can shed pounds without experiencing significant bone loss by eating a low calorie diet that includes essential nutrients...
Thursday Sep 18, 2008
GSK, Cellzome Announce Strategic Alliance to Identify Kinase-Targeted Drugs for Inflammatory Diseases
The alliance gives GSK access to Cellzome’s expertise in identifying and developing selective kinase inhibitors and its proprietary Kinobeads™ technology which, by screening compounds in a physiological setting, is designed to improve the predictability of these drug candidates’ performance in clinical testing...
Tuesday Aug 19, 2008
Cheerleading More Dangerous Than High-Flying Olympic Gymnastics
Cheerleading routines resemble competitive gymnastics ever more closely but are more dangerous, accounting for two thirds of severe sports injuries to female high school and college students, and consuming 25% of the money that the NCAA insurance program spends on student athletes...
Monday Aug 11, 2008
Older Olympians Redefine the Possible in Musculoskeletal Health
This year's summer Olympics athletes are older and may be fitter than those in previous years, and experts say these competitors are redefining musculoskeletal health for the middle-aged and older athletes...
Monday Jul 14, 2008
Adding Caffeine to Carbs Speeds Muscle Glycogen Recovery After Intense Exercise
About 5 or 6 cups of strong coffee ingested along with carbohydrates after intense exercise can increase muscle glycogen recovery by ≥50% versus carbs alone and might prepare athletes for better performance the following day...
Monday Jun 30, 2008
Ghrelin, Leptin Changes Link Menstrual Dysfunction, Bone Health in Teen Athletes
Changes in two hormones that affect both appetite and estrogen secretion appear to be the link between athletic activity, loss of menstrual function, and bone health in some adolescent female athletes...
Wednesday Jun 25, 2008
Exercise Helps Prevent Knee OA in the Young and the Young at Heart
Moderate exercise may help prevent knee osteoarthritis (OA) in young and middle-aged individuals…
Tuesday May 20, 2008
Is "Diarthritis" the New Epidemic? Maybe
We've heard of diabesity (the converging epidemic of diabetes and obesity) and now doctors may be seeing more diarthritis (diabetes plus arthritis) in their patients…
Tuesday May 13, 2008
More than Half of US Diabetics Have Arthritis
Arthritis afflicts more than half of diabetes patients in the US, making exercise difficult…
Thursday May 01, 2008
Cola May Be Bad to the Bones
High consumption of soda may contribute to lower bone mass and the eventual development of osteoporosis…
Wednesday Apr 23, 2008
GSK, Regulus Form Alliance to Develop microRNA-Targeted Therapeutics to Treat RA and IBD; Deal Potentially Valued at Over $600 Million
GlaxoSmithKline and Regulus Therapeutics LLC announced a worldwide strategic alliance to discover, develop, and market novel microRNA(miRNA)-targeted therapeutics to treat inflammatory diseases such as RA and inflammatory bowel disease...
Tuesday Apr 15, 2008
Pain-Fatigue Link May Explain Why FM, CFS Are More Prevalent in Women
A biological link between pain and fatigue may help explain why more women than men are diagnosed with chronic pain and fatigue conditions like fibromyalgia and chronic fatigue syndrome...
Friday Apr 11, 2008
Surprise Findings Suggest OTC Painkillers Help Build Muscle Mass During Weight Training
Taking daily recommended doses of ibuprofen or acetaminophen might boost muscle mass and strength…
Tuesday Apr 08, 2008
Does Physical Therapy Still Have a Place in the Treatment of Ankylosing Spondylitis?
Researchers believe that pharmacological advancements in the treatment of ankylosing spondylitis do not replace traditional physical therapy programs…
Monday Apr 07, 2008
Radius Fills Enrollment of Phase II Trial of BA058 for Osteoporosis in Postmenopausal Women; Milestone Triggers $28.3 Million Financing
Radius Health, Inc announced the completion of patient enrollment in its phase II clinical trial of BA058, an analog of hPTHrP (human parathyroid hormone-related protein)...
Wednesday Apr 02, 2008
DEXA Scans, Serum Testosterone, Vitamin D Tests Urged for Men Over 70
Osteoporosis in men is a common problem and requires more aggressive diagnosis, treatment, and monitoring of response...
Friday Mar 28, 2008
Regeneron’s Arcalyst™ (rilonacept), First and Only FDA-Approved Treatment for Cryopyrin-Associated Periodic Syndromes (CAPS); Now Available in the US
Regeneron Pharmaceuticals, Inc announced that Arcalyst™ (rilonacept) injection for subcutaneous use is now available by prescription in the US for the treatment of cryopyrin-associated periodic syndromes (CAPS)...
Tuesday Mar 18, 2008
'Boot Camps' Treat Pain Sufferers
An intensive 4-week program works to alleviate chronic pain through biological, psychological, and social approaches…
Thursday Feb 28, 2008
Regular Aquatic Exercise Could Benefit Fibromyalgia Sufferers
Adding aquatic exercise 3 times a week to usual care for fibromyalgia may be a cost-effective strategy for improving quality of life...
Monday Jan 14, 2008
8-Week Arthritis Foundation Exercise Program Improves Pain and Fatigue
The Arthritis Foundation Exercise Program, formerly called People with Arthritis Can Exercise (PACE), can safely get older, sedentary arthritis patients up off the couch, a new study shows...
Friday Jan 11, 2008
Localized Strength Training Rx for Neck Pain
Strength training exercises focusing on the neck and shoulder muscles can help relieve chronic neck pain among female workers with trapezius myalgia...
Wednesday Jan 09, 2008
Personalized Exercise Prescriptions Warranted in RA
Individually-tailored exercise programs taking a patient's specific needs and abilities into account should become a standard part of rheumatoid arthritis (RA) treatment. Such programs can help reverse joint damage and reduce cardiovascular risk factors in this population...
Friday Dec 21, 2007
Galapagos to Collaborate With Lilly in OA and to Receive Milestone Payment of €7.5 Million in OA Alliance with GSK
Galapagos NV, an integrated drug discovery company with preclinical programs in bone and joint diseases, announced that it has entered into a global collaboration agreement with Eli Lilly and Co to develop a novel class of medicines with potential to stimulate bone formation for the treatment of osteoarthritis...
Thursday Oct 25, 2007
Galápagos, Janssen Form Global Alliance to Develop Oral Small Molecule Therapeutics for Multiple Targets in RA
Galápagos NV, a drug discovery company with clinical and preclinical programs in bone and joint diseases, announced that it has entered into a worldwide multitarget alliance with Janssen Pharmaceutica NV to discover and develop small molecule therapeutics for the treatment of rheumatoid arthritis (RA)...
Thursday Oct 25, 2007
Systematic Review: Few Signs of Tai Chi Efficacy in RA
Tai chi exercise is often recommended for patients with arthritis, including RA, but a systematic review finds little evidence that it is effective...
Thursday Oct 18, 2007
Coxibs, NSAIDs Have Little Effect on MI Risk
A review of data from RCTs and observational studies found low MI risk with either coxibs or NSAIDs (highest with rofecoxib), and significantly fewer serious upper GI events with coxibs...
Wednesday Oct 17, 2007
Acupuncture Cuts Postop Pain, Opioid Use
Acupuncture should be considered an option for postop pain control among patients after orthopaedic surgery...
Thursday Oct 04, 2007
New Low Back Pain Guidelines Discourage Routine Imaging or Rest for Most Patients
New clinical guidelines for low back pain (LBP) discourage routine imaging in nonspecific LBP, set criteria for diagnostic imaging including MRI, recommend NSAIDs or acetaminophin as first-line drugs, urge the addition of nondrug therapy in difficult cases, and tell physicians to keep patients moving...
Wednesday Oct 03, 2007
Media Miss Point of Acupuncture Back Pain Study
Superficial needling at nonacupuncture points is as good as true acupuncture for relieving chronic low back pain and both are better than conventional therapy, raising the possibility that a "superplacebo effect" accounts for the benefits associated with acupuncture in previous studies...
Monday Oct 01, 2007
Vigorous Exercise May Benefit Knees
Breaking a sweat while exercising at least once a week for around 20 minutes may stave off the development of knee osteoarthritis...
Tuesday Sep 25, 2007
Radius Grants Novartis Exclusive Option to License BA058, an Analog of PTHrP, for Osteoporosis; Potentially Worth Over $500 Million
Radius Health, Inc, a company focused on the discovery and development of drug therapies for osteoporosis and women's health, announced that it has granted Novartis Pharmaceuticals Corp an option to obtain an exclusive worldwide license (except Japan) to develop and commercialize all formulations of BA058, its postmenopausal osteoporosis drug candidate...
Monday Sep 24, 2007
Risk of Infection in TNF-Inhibitor Treatment May Be Higher Than Thought
A new analysis of data from the British Society for Rheumatology Biologics Register suggests that the risk of serious infection is increased during certain phases of TNF-inhibitor treatment...
Friday Sep 14, 2007
Doctors Often Scoff at Reports of Statin Myopathy, UCSD Researchers Say
Myopathy is the most common adverse drug reaction (ADR) reported by patients taking statins, but a new study finds that doctors often wrongly dismiss these reports...Golomb BA, et al. Drug Safety. 2007;30:669-675.
Wednesday Sep 05, 2007
Rheumatologists Asked to Take Lead in Reducing Cardiovascular Risk in RA Patients
The chronic inflammation that characterizes many rheumatoid diseases is thought to be one cause of the higher rates of cardiovascular disease (CVD) that afflicts these patients. Experts say not enough is being done to educate patients with rheumatoid arthritis (RA) or with systemic lupus erythematosus (SLE) about the importance of early CV protection, and that early education is critical—before clinically apparent CVD is detectable...van Leuven SI, et al. Rheumatology. 2007; rheumatology/kem202 [Epub ahead of print]; John H, et al. Rheumatology. 2007; doi:10.1093/rheumatology/kem176 [Epub ahead of print].
Monday Aug 27, 2007
Harkness Dance Medicine Head Urges Clinicians to Prepare for the "High School Musical 2" Generation
Musicals are back, dance classes are filled, clinicians are facing more dancers or former dancers with musculoskeletal problems, and dance medicine experts are urging clinicians to heed the beat of dancing feet...
Thursday Aug 16, 2007
Even Moderate Exercise Improves Outcomes in JIA
Two new studies document diminished aerobic and anaerobic exercise capacity in children and teens with JIA and show that even moderate exercise can markedly improve outcomes...
Wednesday Jul 25, 2007
Hip Protectors Fail to Prevent Hip Fracture in Nursing Home Residents
Energy-absorbing/shunting hip protectors do not protect nursing home residents from hip fractures…Kiel DP, et al. JAMA. 2007;298:413-422.
Wednesday Jul 18, 2007
Brain Function Linked to "Noncontact" Knee Injuries
Differences in brain function may predispose athletes to ACL injury…Swanik CB, et al. Am J Sports Med. 2007;35:943-948.
Friday Jul 13, 2007
Resistance Training Benefits Patients With Myositis
Patients with chronic, stable polymyositis and dermatomyositis can benefit from intensive resistance exercise without suffering increased muscle inflammation...
Thursday Jul 05, 2007
Galapagos Expands OA Alliance With GSK
Galapagos NV, a drug-discovery company with clinical and preclinical programs in bone and joint diseases, announced that is has expanded its existing multiyear osteoarthritis (OA) alliance with GlaxoSmithKline and that it has issued 513,281 new shares for an investment of 4.4 million EUR (approximately 6 million USD) by GSK. In the expanded program, GSK will bring a drug-discovery program against a selected GSK target into the alliance, and Galapagos will advance a disease-modifying drug toward completion of clinical phase IIa (proof-of-concept phase), at which point GSK's global research and development branch will be responsible for the late-stage development, production, and marketing of the drug...
Monday Jun 04, 2007
Is Resistance Exercise the Fountain of Youth?
Resistance training may help reverse aging in skeletal muscle by altering mitochondrial function among healthy seniors...
Tuesday May 29, 2007
Biomechanics, Damage Outside Cartilage May Doom Chondroprotection
Chondroprotection seemed like a reasonable approach to OA when the disease was thought to result from wear and tear on cartilage, but it has had little success in clinical trials. Biomechanics and damage outside the cartilage may be the reason...
Thursday May 10, 2007
Hydrotherapy, Tai Chi May Be Better Than Traditional Land-Based Exercises for OA
Hydrotherapy and Tai Chi are both better at improving physical function in OA patients than traditional exercise programs, and hydrotherapy has a particularly high patient adherence, perhaps because it seems to provide greater pain relief...
Wednesday May 02, 2007
Novosom Acquires Exclusive License Option for CD40-Targeted Antisense Inhibitors from Isis; Deal Strengthens Inflammation Therapeutic Development Program
Novosom AG announced that it has purchased an exclusive option from Isis Pharmaceuticals, Inc (CARLSBAD, California) that, if exercised within 6 months, enables the company to acquire an exclusive, worldwide license to antisense inhibitors targeting the CD40 receptor for all indications...
Thursday Apr 26, 2007
Balance Training May Help Reverse Frailty, Prevent Osteoporosis-Related Fractures
Balance training alone or in combination with strength, agility and jumping training can reduce the risk of falls and prevent frailty in women at risk of osteoporosis…
Thursday Apr 12, 2007
Dropping 5% of Weight in 20 Weeks Reduces Disability, Pain in Knee OA
Losing just 5% of total body weight within a 20-week period — or 0.25% per week — should be enough for overweight or obese patients with knee OA to feel and function better. . .
Wednesday Apr 11, 2007
La Jolla Pharmaceutical Company to Net Approximately $38 Million in Public Offering
La Jolla Pharmaceutical Company, a clinical-stage pharmaceutical company focused on autoimmune and inflammatory disorders, announced the receipt of estimated aggregate net proceeds of approximately $38 million from the recently completed underwritten public offering of 5,800,000 shares of its common stock, including the expected proceeds from an exercised overallotment option to the underwriters to purchase an additional 870,000 shares...
Wednesday Jan 31, 2007
First, Do No Harm—Exercise Won't Up Risk of Knee OA
Exercise neither protects against nor increases the risk of knee osteoarthritis (OA) in older, overweight adults…
Tuesday Jan 23, 2007
Can the Web Help Doctors Get RA Patients Moving? Maybe
RA patients randomized to an individualized, Internet-based exercise program report more physical activity than those given general exercise information, but the electronic monitor does not confirm their reports...
Tuesday Jan 16, 2007
FDA Sets New Rule on Calcium/Vitamin D Osteoporosis Claims for Food, Diet Supplement Labeling
The FDA will permit a new "calcium plus vitamin D" claim in food and dietary supplement labeling for reducing the risk of osteoporosis and will shorten the required label in the hope that more dairy, juice, and other products that qualify will put it on their packaging, thus increasing consumer awareness...
Wednesday Jan 03, 2007
Nuvo Receives Approvable Letter from US FDA for Pennsaid, a Topical Nonsteroidal Anti-Inflammatory for the Treatment of Osteoarthritis of the Knee; Nuvo Licenses Canadian Pennsaid Plus Rights to Squire Pharmaceuticals, a Subsidiary of Paladin Labs
Nuvo Research Inc announced that it has received an approvable letter from the US FDA for Pennsaid® (1.5% w/w diclofenac sodium solution), a topical nonsteroidal anti-inflammatory (NSAID) for the treatment of osteoarthritis (OA) of the knee.
Wednesday Nov 22, 2006
Still No Final Word on Diskectomy vs Nonoperative Treatment for HNP
New data show no dramatic difference between diskectomy and nonoperative management of lumbar disk herniation—suggesting that individual patient preferences should play a major role in choice of treatment— and that there is no great risk in delaying surgery.
Wednesday Nov 01, 2006
Community Physiotherapy, Pharmacy Review Can Help Knee OA Patients Reduce NSAID Use
Physiotherapists and pharmacists can safely and effectively deliver evidence-based care to patients with knee pain resulting in improvements in pain, high degree of patient satisfaction, and reduced use of nonsteroidal anti-inflammatory drugs, at least in the short term...
Thursday Oct 26, 2006
New Study Casts Doubt on Metabolic Dysfunction in Chronic Fatigue Syndrome
A new study comparing response to exercise in patients with chronic fatigue syndrome (CFS) and fibromyalgia (FM) finds exercise more difficult in CFS/FM patients than in those with CFS alone, but casts doubt on metabolic explanations for CFS…Cook DB, et al. Arthritis Rheum. 2006;54:3351–3362.
Thursday Oct 19, 2006
Conventional strength training program has little effect on knee OA progression
Conventional strength training exercises have little effect on progression of knee osteoarthritis... Mikesky AE, et al. Arthritis Care & Research 2006;55:690-693.
Wednesday Aug 02, 2006
Fear of Pain Robs Arthritis Patients of Chance for Pain-Relieving Exercise
Fear of pain is a major reason people with arthritis avoid exercise, and many are unaware that regular exercise can reduce pain and prevent disability. …Wilcox, S, et al. Arthritis Care Res. August 2006; DOI: 10.1002/art.22098
Tuesday Jun 27, 2006
Bosentan Prevents Digital Ulcers, Improves Heart Function in Systemic Sclerosis
Bosentan reduces digital ulcer risk and improves heart function in systemic sclerosis patients... Allanore Y, et al. Presented at: EULAR 2006 Meeting; June 21–34, 2006; Amsterdam, The Netherlands. Abstract OP0120.
Friday Jun 23, 2006
Kyphoplasty Reduces Osteoporotic Fracture Pain, but Does It Predispose to More Fractures?
Pharmacologic treatments for osteoporosis leave up to 50% of patients suffering long-term pain from fractures—perhaps unnecessarily... Kasperk C. Presented at: EULAR 2006; June 21–24, 2006; Amsterdam, The Netherlands. Abstract SP0033.
Thursday Jun 22, 2006
EULAR Lupus Guidelines Make the Best of Sparse Data
While EULAR experts agree on the best treatment of SLE and recommend an integrated approach to medical care, the lupus task force also warns of a worrying lack of evidence on the benefits of lifestyle modifications and the impact of primary preventive measures... Boumpas D. 2006 EULAR Meeting.
Wednesday Jun 21, 2006
EULAR Fibromyalgia Recommendations Surprisingly Upbeat
Far from being a hard-to-treat condition, fibromyalgia is yielding to a whole range of pharmacological and nonpharmacological therapies, according to a review presented by Ernest H. Choy, MD, at the 2006 EULAR Meeting...
Tuesday May 02, 2006
Exercise, Weight Loss Can Reverse Frailty in Obese Elderly
Diet-induced weight loss and exercise training can significantly strengthen and protect obese older adults and should be considered primary therapy in frail obese older patients... Villareal DT, et al. Arch Intern Med. 2006;166:860-866.
Friday Feb 17, 2006
Calcium With Vitamin D Does Not Decrease Risk of Hip Fracture in Postmenopausal Women
Calcium with vitamin D does not decrease risk of hip fracture and only shows a modest benefit in bone density... Jackson RD, et al. New Engl J Med. 2006;354:669-683.
Wednesday Jan 18, 2006
Human Genome Sciences to Advance LymphoStat-Bâ„¢ to Phase III in Lupus
Human Genome Sciences, Inc, announced plans to initiate in 2006 a phase III clinical trial of LymphoStat-Bâ„¢ (belimumab)...
Monday Jan 09, 2006
Yoga Superior to Self-Care Book or Regular Exercise for Low Back Pain
Yoga is more effective than either instruction from a self-care book or a traditional exercise program at improving function and reducing medication use among patients with chronic low back pain. Sherman KJ, et al. Ann Intern Med. 2005;143:849-856.
Monday Oct 31, 2005
Regular Physical Activity May Strengthen Knee Cartilage
A novel magnetic resonance imaging technique used in a new study suggests that human articular cartilage can adapt to physical load, and that modest exercise improves knee cartilage glycosaminoglycan content in patients at risk for developing osteoarthritis … Roos EM, Dahlberg L. Arthritis Rheum. 2005;52:3507-3514.
Thursday Oct 06, 2005
Human Genome Sciences' LymphoStat-Bâ„¢ for Lupus Fails to Meet Primary Endpoints in Phase II Trial
Human Genome Sciences, Inc (Rockville, Md), announced that its investigational drug for lupus, LymphoStat-Bâ„¢, (belimumab) failed to meet the overall primary efficacy endpoints...
Sunday Aug 21, 2005
Schering-Plough and Centocor to Codevelop Monoclonal Antibody Against TNF-α
Schering-Plough Corporation has announced that it has exercised its rights to develop and commercialize...
Monday Jul 18, 2005
GSK and HGS to Jointly Develop LymphoStat-BTM for RA and Lupus
Human Genome Sciences, Inc. (HGS) announced that GlaxoSmithKline (GSK) has exercised its option under a 1996 agreement to co-develop and commercialize LymphoStat-B (belimumab), a human monoclonal antibody (created through a collaboration with Cambridge Antibody Technology) that neutralizes the activity of B-lymphocyte stimulator, or BlySTM, a protein required for the development of B-lymphocytes into mature plasma B cells.
Tuesday Jul 12, 2005
Structural Changes in Femoral Neck Increase Risk of Hip Fracture
Walking may not be enough to strengthen the hip; instead, it may be necessary to develop exercises that target the superolateral cortex of the femoral neck, which is often associated with fractures from sideways falls... Mayhew PM, et al. Lancet. 2005;366:129-135.
Friday Jul 08, 2005
Weight Loss Reduces Knee Joint Load
Losing just one pound results in a four-fold reduction in knee joint load in overweight and obese patients with OA of the knee... Messier SP, et al. Arthritis Rheum. 2005;52:2026-2032.
Thursday Jun 09, 2005
Study Helps Clarify Link Between RA and CVD
Il-6, rheumatoid factor, and chronic kidney disease predict endothelial dysfunction among RA patients and need to be suppressed to stave off atherosclerosis...Presented at: Annual European Congress of Rheumatology of EULAR; June 8-11, 2005; Vienna, Austria.
Tuesday May 24, 2005
Rehabilitation Is as Beneficial and More Cost-Effective Than Spinal Fusion in Chronic Low Back Pain Patients
Contrary to previous reports and often physicians' advice, rehabilitation utilizing cognitive behavior principles is as effective as fusion for chronic low back pain, and should be offered as a first-line therapy...Fairbank J, et al. BMJ. May 23, 2005; [Epub ahead of print].
Monday May 16, 2005
Higher Doses of Vitamin D May Reduce Risk of Fractures in the Elderly
In contrast to several recently published studies showing that regular supplements of calcium and vitamin D may not effectively prevent fractures, a newly published meta-analysis found that large doses of vitamin D-taken with or without calcium-reduce the risk of nonvertebral fractures in the elderly...Bischoff-Ferrari HA, et al. JAMA. 2005;293:2257-2264
Tuesday May 10, 2005
Exercise Benefits Chronic, but Not Necessarily Acute Nonspecific Back Pain
Two meta-analyses reveal that for lower back pain lasting longer than 6 weeks, individualized exercise therapy programs are effective for reducing pain and improving function...Hayden, JA et al. Ann Intern Med. 2005;142:765-775
Wednesday Mar 30, 2005
Cognitive-Behavioral Program Helps OA Patients Feel and Function Better
A self-management program that teaches goal setting, self-relaxation, and other behavioral measures improves pain and self-reported function in Dutch cohort... Heuts PH, et al. J Rheumatol 2005;32:543-549.
Friday Feb 25, 2005
Obese and Overweight Patients Tend to Gain Weight After Lower Extremity Arthroplasty
A new study counters the assumption that obese and overweight patients with hip or knee arthritis will lose weight after arthroplasty...72nd Annual Meeting of the American Academy of Orthopaedic Surgeons, February 23-27, 2005.
Friday Feb 25, 2005
The Future of Spinal Surgery: Artificial Discs and Bone Growth Factors Show Promise
PCM cervical discs, Charité lumbar discs, and BMPs demonstrate improved outcomes and greater patient satisfaction as alternatives to traditional spinal fusion surgery...72nd Annual Meeting of the American Academy of Orthopedic Surgeons; February 23, 2005.
Friday Feb 18, 2005
European Medicines Agency Calls Cardiovascular Risk a Class Effect of Coxibs
EMEA calls for stricter labeling and restricted use for COX-2 inhibitors... will the FDA follow suit? EMEA press release. London, UK; February 17, 2005.
Tuesday Jan 25, 2005
Three New Studies Further Elucidate Risks and Benefits of Coxibs
Newly published study findings from CRESCENT show that rofecoxib significantly increases 24-hour blood pressure after 6 weeks of therapy, while celecoxib and naproxen do not; two other published studies address COX-2 risks and benefits... Sowers JR, et al. Arch Intern Med. 2005;165:161-168.
Wednesday Nov 24, 2004
Gender Bias May Exist in the Recognition and Treatment of Osteoporosis in Men
Although men have higher vertebral fracture rates than women, they may not get screening and treatment for osteoporosis as often or as early... Sawka AM, et al. J Rheumatol. 2004;31:1993-1995.
Tuesday Nov 16, 2004
Long-Term, High-Intensity Aerobic Exercise May Benefit the Joints of the Feet
Contrary to the perception that an intensive, weight-bearing exercise regimen increases the rate of radiological joint damage of the hands and feet in patients with rheumatoid arthritis, a Dutch study suggests that a long-term, high-intensity program that results in improvement in aerobic fitness and involves 'impact-generating' activities may in fact have a protective effect on the joints of the feet. DeJong Z, et al. Ann Rheum Dis . 2004;63:1399-1405.
Thursday Oct 21, 2004
Researchers Outline Genetic and Environmental Triggers for Virulent Ankylosing Spondylitis
Genetic predisposition and a physically demanding job affect extent of disability that will accompany the inflammatory disease... Ward MM, et al. Presented at: Annual Meeting of the American College of Rheumatology; October 20, 2004; San Antonio, Tex.
Tuesday Aug 31, 2004
Primary Care Physician Survey Shows Back Pain Highly Prevalent, Often Involves Spasm
Acute back injuries often have a spasmodic as well as an inflammatory component; treating both expedites recovery.
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