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Found 130 result(s) FROM 1963 pages containing the term 'imaging'.
Wednesday Feb 10, 2010
FDA Wants to Reduce Radiation Exposure from Medical Scans
Widespread use of CT scans and fluoroscopy is exposing some patients to unnecessary amounts of radiation, and raising their risk of cancer...
Thursday Nov 05, 2009
Feds Set to Cut 21.5% from Medicare Fees—Before Healthcare Reform
The new Medicare Physician Fee Schedule will, overall, cut physician's fees by 21.5% in 2010...
Wednesday Oct 28, 2009
Third RA Patient Has PML After Rituximab
The FDA's MedWatch warning system reports that a third rheumatoid arthritis (RA) patient treated with Genentech's Rituxan (rituximab) has developed PML, this time without prior anti-TNF exposure...
Thursday Oct 15, 2009
To Scope or Not to Scope in Hip Patients Over 60
Hip arthroscopy may benefit some patients aged 60 and older with femoroacetebular impingement...
Thursday Oct 01, 2009
MRI Can Show Joint Damage in Early Gout
For patients with gout but normal plain radiographs, MRI is more sensitive than ultrasound for detecting early gout, but what to do with that information is unclear...
Tuesday Sep 29, 2009
Fibromyalgia Goes Legit
Better understanding of the brain chemistry anomalies in fibromyalgia have paved the way toward more effective treatments for this pain disorder...
Thursday Sep 24, 2009
Rituximab Improves SSc Lung Function
A small pilot study has established proof-of-principle that rituximab improves lung function in scleroderma...
Thursday Jul 09, 2009
EULAR Reports Link High Glutamate to Fibromyalgia Pain
Two studies on glutamate in brains of fibromyalgia patients show abnormal levels of the neurotransmitter in areas related to pain perception and emotional processing...
Wednesday Jun 24, 2009
RA Rituxan Response Seen Best with High Res US
High resolution grey-scale ultrasonography may help rheumatologists measure response to rituximab treatment in rheumatoid arthritis (RA) patients...
Tuesday Jun 02, 2009
Imaging Overused for Low Back Pain in Elderly
X-rays or advanced imaging scans to detect the source of low back pain are overused for certain elderly patients, mainly those treated in large practices that offer patient satisfaction-based financial incentives...
Thursday May 14, 2009
Could a Urine Test Identify Early OA?
Separate sets of collagen degradation markers can differentiate very early knee OA from knee pain that is not due to OA...
Wednesday May 13, 2009
Persistent Sore Ankle Might Be Damaged Tendon
Physicians should consider peroneal tendon injury in patients with refractory lateral ankle pain...
Monday Apr 13, 2009
Caffeine May Be New Rx for Pain-Free Exercise
Jumpstarting a workout with a jolt of java or another readily available caffeinated beverage may reduce the pain associated with exercise...
Thursday Apr 02, 2009
Back Pain: Too Little Exercise, Too Much Imaging
Patients with low back pain are using too many ineffective treatments and too few of those proven effective...
Tuesday Mar 31, 2009
As CT Radiation Accumulates, Cancer Risk May Rise
Cumulative radiation exposure from CT scans can raise cancer risk by up to 12%...
Thursday Mar 26, 2009
Firefly Protein Lights Up Lupus Imaging
Bioluminescent imaging of NF-kB pinpoints inflamed sites long before symptoms appear in a mouse model of lupus and is likely to speed development of treatments for early disease...
Monday Mar 16, 2009
Chondrolysis Seen With Local Anesthetic After Shoulder Surgery
Local anesthetic infused into the shoulder joint after arthroscopy can destroy shoulder cartilage...
Monday Feb 09, 2009
Scans for Back Pain Ineffective
Imaging scans are largely ineffective at locating the source of low back pain, and may do more harm than good…
Friday Jan 23, 2009
Shoulder Pain Imaging: Arthrography Not Always Needed
Arthrography adds important information to 3-T conventional MRI only in a subset of shoulder pain cases...
Wednesday Jan 14, 2009
Wrist MRI Lets Many Avoid Arthroscopy
3-T MRI of the wrist effectively detects wrist ligament tears and may help patients avoid unnecessary surgery...
Wednesday Dec 17, 2008
Early RA Shows as MRI Hand Tenosynovitis
MRI readily detects early arthritis as flexor tenosynovitis...
Friday Dec 12, 2008
Cartilage Repair Moving from Bench to Bedside
Mosiacplasty may soon be the method of choice for orthopaedic surgeons treating small focal defects in cartilage, but stem cell-based cartilage repair is also moving stealthily down the pike...
Tuesday Dec 09, 2008
OA Imaging Explains Subchondral Cysts, Bone Marrow Edema
New OA imaging studies support the bony contusion theory of subchondral cyst formation and show that bone marrow edema in the medial tibia, but not other sites, is a good marker for OA severity...
Monday Nov 17, 2008
Vitamin D Levels Linked to OA Cartilage Loss, OA Pain, and SSc Disease Activity by ACR Researchers
Low vitamin D levels are associated with faster progression of joint damage, bone loss, and pain in OA and with higher levels of inflammatory markers and vascular complications in systemic sclerosis, suggesting that more attention to vitamin D supplements might be in order...
Friday Nov 07, 2008
Studies Confirm, Extend Uses of MRI in Spondyloarthropathies
Severe romanus lesions in patients with back pain who are younger than 51 are very specific for spondyloarthropathy, and an MRI of just the sacroiliac joint is generally enough to diagnose nonradiographic axial SpA, regardless of the location of the back pain...
Thursday Oct 16, 2008
The Scan That Didn’t Scan
Both doctors and patients rely heavily on findings from MRI scans, but the quality of MRI can be erratic and not always reliable…
Thursday Oct 09, 2008
Rheumatologists Usually on Target With Intra-Articular Injections, Even Without Ultrasound
New research shows that blind intra-articular injections (IAIs) in rheumatoid arthritis patients, done without ultrasound guidance, are accurate when performed by a trained rheumatologist. Blind injections into the ankle are the most unreliable, at 77% accuracy...
Monday Sep 22, 2008
Body Fat Increases CRP in Women With RA, May Lead to Wrong Diagnosis of Persistent Synovitis
High levels of adipose tissue, especially in the midsection, are associated with high CRP levels in women with RA. Elevated CRP levels in overweight patients might not be an indication that more aggressive RA treatment is needed...
Wednesday Sep 17, 2008
Experts Warn the Meniscal Damage Seen on MRI Should Not Drive Knee Surgery Decisions in Middle-Aged, Elderly Persons
Most middle-aged and elderly persons who have meniscal damage that can be seen on MRI have asymptomatic knees, and even in those with symptoms, the pain might not be related to the meniscus...
Monday Sep 15, 2008
Study Rules Against Arthroscopy for Most Knee OA Cases
Arthroscopy is not effective for the treatment of knee osteoarthritis (OA), but an editorialist urges clinicians not to throw out the baby with the bathwater as arthroscopy can—and does—help knee OA patients in whom a coexisting knee problem such as a meniscal tear or a loose piece of cartilage is causing the majority of their symptoms…
Thursday Sep 04, 2008
“Good Bugs” Offer New Way to Turn Down Inflammatory Response
“Probiotic” helpful bacteria might be able to turn down the body's inflammatory response...
Friday Aug 29, 2008
Ligaments Tie Together OA Pathology
Ligaments are emerging as the key to understanding why osteoarthritis develops in nontraumatized joints...
Wednesday Aug 27, 2008
Researchers Home in On Role of TNF in RA Bone Destruction
Tumor necrosis factor alpha (TNFα) decreases osteoblast numbers via an enzyme called Smad Ubiquitin Regulatory Factor 1 (SMURF1), which shuts down two proteins that would otherwise drive bone formation…
Monday Aug 18, 2008
Power Doppler Ultrasound Measures Response to TNF-blockers in RA
Power doppler ultrasonographic monitoring may help measure response to TNF-blockers as well as predict X-ray progression in rheumatoid arthritis (RA) patients…
Friday Jul 25, 2008
New High-Resolution Device Aids Finger MRI in Scleroderma
High-resolution magnetic resonance angiography (micro-MRA) can readily measure vascular disease of fingers in systemic sclerosis…
Thursday Jul 24, 2008
Quantitative Imaging of Musculoskeletal Tissue
Quantitative imaging of musculoskeletal tissue is now the essential methodology in clinical practice for diagnosis and monitoring various musculoskeletal diseases
Thursday Jul 03, 2008
Heel Ultrasound Improves Osteoporosis Diagnosis
A heel quantitative ultrasound coupled with an assessment of specific osteoporosis-related risk factors in patients can help doctors predict fracture risk and decide who would need further screening with dual-energy X-ray absorptiometry (DXA)…
Friday Jun 20, 2008
Longitudinal MRI Study Confirms that Rituximab Stops Progression in RA, Suggests Some Regression
Imaging studies done 1 year after rituximab (RTX) treatment for rheumatoid arthritis (RA) confirm that progression of joint damage was stopped, and suggest that there may even have been some regression of established damage...
Wednesday Jun 18, 2008
Rigel Launches Two Global Phase IIb Clinical Trials of Syk Inhibitor, R788 (fostamatinib disodium), in RA
Rigel currently has small-molecule product development programs in inflammatory/autoimmune diseases such as rheumatoid arthritis, thrombocytopenia, and asthma...
Thursday Jun 12, 2008
Sound, Pressure Show General CNS Sensory Changes in FM
FM patients have a general CNS augmentation of sensory information, not just abnormal pain processing...
Wednesday Jun 11, 2008
Meniscal Damage, Joint Malalignment Predict Cartilage Loss in Knee OA
New research confirms that meniscal damage and joint alignment predict cartilage loss in knee osteoarthritis (OA)…
Wednesday Jun 04, 2008
Case Series Adds Support for Routine PET in Polymyalgia Rheumatica
Routine PET might be a useful option in patients with steroid-resistant polymyalgia rheumatica (PMR)...
Thursday Apr 24, 2008
S. pyogenes-Linked New-Onset Childhood Arthritis Differs in Severity, Duration, from Other Types
Up to 35% of children with new-onset arthritis test positive for S. pyogenes and have a different disease course than children with other forms of inflammatory arthritis; they do not need routine cardiology follow-up, according to a population-based study...
Friday Apr 11, 2008
Surprise Findings Suggest OTC Painkillers Help Build Muscle Mass During Weight Training
Taking daily recommended doses of ibuprofen or acetaminophen might boost muscle mass and strength…
Wednesday Apr 09, 2008
TMJ in Juvenile Idiopathic Arthritis May Require MRI for Diagnosis, But it Can Heal
TMJ damage in children with JIA can resolve with actual healing of the damaged condyles once the underlying disease is controlled, but MRI might be required to diagnosis the jaw disorder...
Wednesday Mar 05, 2008
AAOS Researchers Provide New Look at Steroid-Induced Osteonecrosis
Steroid-induced osteonecrosis tends to resolve in SLE patients when the underlying disease is under control but tends to advance after SLE recurs. In patients with steroid-induced hip osteonecrosis, shoulder damage is likely to result in joint collapse within 15 years if not treated...
Tuesday Feb 19, 2008
Big-Time Injury Strikes Little Players
An increasing number of child and adolescent athletes are being diagnosed with torn ACLs...
Thursday Jan 17, 2008
Too Much of a Good Thing?
Growing use of CT scans is causing concern about radiation exposure...
Thursday Jan 03, 2008
Practice Tips: Using Color or Power Doppler Ultrasound in Rheumatology
Danish researchers have proposed settings for Doppler ultrasound (US) designed to improve detection of inflammation, visualized as hyperemia in locations such as the synovial membrane...
Thursday Dec 20, 2007
OARSI Researchers Further Refine Matrix-Associated Cartilage Repair Techniques
Matrix-associated autologous chondrocyte implantation continues to improve as a way of repairing arthritis knees, and MRI can be used to check the quality of the repaired tissue...
Wednesday Dec 19, 2007
Synovitis, Effusion, Bone Marrow Lesions Tagged As Modifiable Factors in Knee Pain
Knee pain fluctuation correlates with changes in several modifiable MRI features: synovitis, effusion, and bone marrow lesions...
Monday Dec 17, 2007
Pain in Knees with Meniscal Damage is Due to OA
Knee pain in middle-aged and older adults who have meniscal damage is due to the osteoarthritis (OA) that often develops in such knees, not to pain from the torn meniscus...
Thursday Dec 13, 2007
MRI Bone Edema Shows Differences, Similarities in RA and OA
MRI bone edema predicts radiographic progression in RA and correlates with pain in OA...
Wednesday Dec 05, 2007
Drug Update: Infliximab
Researchers offer advice on reducing infliximab infusion times in RA, predicting who will respond, and what to expect in patients with ankylosing spondylitis...
Friday Nov 09, 2007
RA Ages and Taxes the Heart
More than half of 50 to 59 year olds newly diagnosed with RA and those >e;60 years have a >e;10% risk of developing heart disease within the next 10 years. Cardiovascular risk reduction strategies are recommended...
Monday Nov 05, 2007
Lab-on-a-Chip Promises Fast Profile of RA Patients' Autoantibodies
A new technique promises fast, inexpensive serum antibody profiling in RA patients without the need for fluorescent labeling or preprocessing...
Monday Oct 15, 2007
Enlarging Bone Marrow Lesions Add to Knee Pain
Research shows that new onset knee pain was strongly linked with an increase of two or more units in bone marrow lesions...
Thursday Oct 04, 2007
New Low Back Pain Guidelines Discourage Routine Imaging or Rest for Most Patients
New clinical guidelines for low back pain (LBP) discourage routine imaging in nonspecific LBP, set criteria for diagnostic imaging including MRI, recommend NSAIDs or acetaminophin as first-line drugs, urge the addition of nondrug therapy in difficult cases, and tell physicians to keep patients moving...
Monday Oct 01, 2007
Vigorous Exercise May Benefit Knees
Breaking a sweat while exercising at least once a week for around 20 minutes may stave off the development of knee osteoarthritis...
Thursday Sep 27, 2007
Panel Issues New Guidelines for Use of Imaging in Ankylosing Spondylitis
Although standard X-rays are essential for diagnosis and MRI may help diagnose early cases before radiographic damage develops, no form of imaging is yet useful for monitoring response to treatment or for routine monitoring of disease progression in AS, experts say...
Monday Aug 27, 2007
Harkness Dance Medicine Head Urges Clinicians to Prepare for the "High School Musical 2" Generation
Musicals are back, dance classes are filled, clinicians are facing more dancers or former dancers with musculoskeletal problems, and dance medicine experts are urging clinicians to heed the beat of dancing feet...
Friday Aug 17, 2007
Mayo Researchers Shake, Blast Biofilms to ID Bacteria Infecting Joint Prostheses
Mayo Clinic researchers have developed a new test that identifies organisms infecting joint prostheses more accurately than sampling tissue around the joint at the time of resection...Trampuz A, et al. N Engl J Med. 2007;357:654-663.
Thursday Aug 09, 2007
Calcitonin Study Heightens Interest in Antiresorptive Agents to Prevent OA Joint Damage
Calcitonin prevents the development of OA in an animal model and adds to evidence that antiresorptive agents can protect both cartilage and bone...
Thursday Jun 28, 2007
Knee OA Synovitis Linked To Pain but Not To Cartilage Loss
Longitudinal MRI shows that changes in knee synovitis correlate with pain but not with cartilage loss in knee OA and suggest that treatment targeted to synovitis may improve pain…
Wednesday Jun 13, 2007
Stopping AS May Require Earlier Use of TNF-Inhibitors
Inflammation in AS stops once the subchondral bone is eroded and the bone/cartilage interface disappears, so preventing bone erosion and syndesmophyte formation is likely to require early anti-inflammatory treatment, including TNF-inhibitors...
Thursday May 31, 2007
Smoking Leads to Knee Cartilage Loss in Individuals With Family History of OA
Smoking leads to loss of knee cartilage and increased development of cartilage defects in individuals who have at least one parent with severe knee OA...
Tuesday May 29, 2007
Biomechanics, Damage Outside Cartilage May Doom Chondroprotection
Chondroprotection seemed like a reasonable approach to OA when the disease was thought to result from wear and tear on cartilage, but it has had little success in clinical trials. Biomechanics and damage outside the cartilage may be the reason...
Tuesday May 15, 2007
Echorheumatology: Will Growing Interest in Musculoskeletal Ultrasonography Result in a New Subspecialty?
UK rheumatologists sound off on some of the barriers to in-office ultrasonography...
Tuesday May 08, 2007
2-Year Results Support Use of New Chondrocyte Graft to Repair Knee OA Damage
Two-year follow-up of a new 3-dimensional scaffold that permits grafting of autologous chondrocyte to repair knee cartilage defects show promising results in both knee OA and knee trauma, and the procedure can be done arthroscopically...
Tuesday May 01, 2007
MRI Erosions, Edema in RA Are Due to Inflammatory Infiltrates in Bone Marrow
Bone erosions and bone marrow edema seen with MRI in joints affected by RA are due to inflammatory infiltrates that have invaded the bone marrow...
Tuesday Mar 13, 2007
Experts Hope Ultrasound and MRI Will Get More Gout Patients Into Treatment
In-office ultrasonography and greater use of MRI might improve gout diagnosis, simplify monitoring of response to urate-lowering therapy, and inspire more aggressive use of hypouricemic agents...
Monday Mar 05, 2007
New Study Suggests MRI Might Be Alternative to Radiographic JSW as Efficacy Measure for Osteoarthritis Drugs
Radiographic JSW remains the gold standard for assessing progression of knee OA in clinical trials, but new research suggests that MRI might be a reasonable alternative...
Thursday Mar 01, 2007
Calcium-Containing Crystals May Contribute to OA Joint Destruction, Be Amenable to Treatment
Evidence is accumulating that calcium-containing crystals, which are common in OA synovial fluids in some patients, contribute to the development of rapidly destructive arthritis and might be a target for therapeutic intervention...
Tuesday Feb 20, 2007
Osiris's Chondrogenâ„¢ Adult Stem Cell Therapy Fails to Demonstrate Cartilage Regeneration According to Interim Results from Phase I/II Study
Osiris Therapeutics, a leader in adult stem cell therapy, announced that 6-month interim results from its phase I/II clinical study of Chondrogenâ„¢, a preparation of mesenchymal stem cells obtained from the bone marrow of healthy adult donors and specially formulated for direct injection into the knee for the regeneration of the meniscus in the knee and prevention of osteoarthritis, failed to demonstrate significant amounts of meniscal regeneration...
Wednesday Jan 31, 2007
First, Do No Harm—Exercise Won't Up Risk of Knee OA
Exercise neither protects against nor increases the risk of knee osteoarthritis (OA) in older, overweight adults…
Thursday Jan 11, 2007
New Study Challenges Role of Low Vitamin D in OA Worsening
Low vitamin D levels did not predict worsening of knee OA joint space narrowing or cartilage loss...
Wednesday Jan 03, 2007
The Change in (Chronic) Pain Is Plainly in the Brain
Patients with chronic lower back pain show imaging changes in the cingulate gyrus, postcentral gyrus, and prefrontal cortex...
Friday Dec 22, 2006
New Studies Suggest That Autoantibodies Damage Brain, Cause Cognitive Impairment in SLE Patients
The cognition and mood disturbances common in lupus patients might be due in part to autoantibodies that target the NMDA receptor and cause progressive damage of the amygdala and hippocampus...
Tuesday Dec 19, 2006
FDA Warns of Fatal PML Risk With Rituximab Treatment
FDA reports deaths of two lupus patients treated with rituximab, warns of PML risk...
Monday Dec 18, 2006
Smoking Exacerbates Knee OA
Men with knee osteoarthritis (OA) who smoke experience greater cartilage loss and more severe pain than men who do not smoke…Amin S, et al. Ann Rheum Dis. 2006 December 20; [Epub ahead of print].
Wednesday Dec 13, 2006
RA Remission Often Accompanied by Silent Synovitis
The majority of rheumatoid arthritis (RA) patients who meet ACR remission criteria still have synovitis detectable on MRI or ultrasound...
Thursday Dec 07, 2006
Leaning Back Might Help the Desk-Bound Dodge Back Pain
A positional MRI study of sitting postures and intervertebral disk morphology suggests that leaning back a bit rather than sitting up straight or slouching can greatly reduce strain on the lumbar spine and cut the risk of chronic back pain...
Wednesday Dec 06, 2006
Serum MMP-3 May Be Biomarker of Joint Damage in AS, MRI Accuracy Questioned
Measuring serum levels of metalloproteinase 3 (MMP3) may be an inexpensive yet accurate way for rheumatologists to predict which AS patients will develop joint damage, particularly in those with pre-existing radiographic damage...
Wednesday Nov 22, 2006
Still No Final Word on Diskectomy vs Nonoperative Treatment for HNP
New data show no dramatic difference between diskectomy and nonoperative management of lumbar disk herniation—suggesting that individual patient preferences should play a major role in choice of treatment— and that there is no great risk in delaying surgery.
Wednesday Nov 15, 2006
Is Resection Necessary? Meniscal Tears Rarely Cause Pain
Meniscal resection may do little to relieve pain among older patients with knee osteoarthritis (OA), as meniscal tears are common but rarely cause any symptoms... Englund M, et al. Presented at ACR 2006 Meeting.
Wednesday Oct 25, 2006
NSAIDs/DMARDs Can Thwart Antibiotic-Refractory Lyme Arthritis
Report highlights effective postantibiotic strategies for treating antibiotic-refractory Lyme arthritis and identifies risk factors for the rare but vexing condition... Steere AC, Angelis SM. Arthritis Rheum. 2006;54:3079-3086
Tuesday Oct 03, 2006
FRISK Score Seen As Alternative to T- or Z-Score for Predicting Fracture Risk
The Fracture Risk (FRISK) Score was developed to predict fracture more accurately than bone mineral density alone, but questions have been raised about its clinical usefulness... Henry MJ, et al. Radiology. 2006:241:190-196.
Monday Sep 11, 2006
Small, Portable In-Office MRI Can Monitor Response to Therapy in RA
As RA treatments become more effective and expensive, monitoring response to therapy becomes more important. Two new studies suggest that small, portable MRI devices might help...
Friday Sep 01, 2006
NMDA Receptor Antibodies Tied to Depression in Lupus, But Not to Cognitive Changes
Anti-NR2 antibodies, which target the NMDA receptor, are associated with depression in patients with lupus but not with cognitive dysfunction... Lapteva L, et al. Arthritis Rheum. 2006;54:2505-2514.
Thursday Aug 24, 2006
Apparent Changes in Joint Space Often Due to Changes in the Meniscus
New research suggesting that alterations in the meniscus contribute a large proportion to variations in joint space narrowing (JSN) may have ramifications for how clinical trials of disease modifying osteoarthritis drugs are conducted... Hunter DJ, et al. Arthritis Rheum. 2006;54:2488-2495.
Thursday Aug 17, 2006
Early Diagnosis of AS: Dr. Rudwaleit Does the Math to Make It Easy
Diagnosing early ankylosing spondylitis in a patient with chronic back pain may be easier with a simple method based on standard tests and symptoms... Rudwaleit M, et al. Ann Rheum Dis. 2006;65:1251-1252.
Saturday Jul 08, 2006
New Study Supports Steroid Injections for Hip OA
Data from a new randomized, controlled trial support the EULAR recommendation on steroid injections for hip OA....Lambert RG, et al. EULAR 2006.
Friday Jul 07, 2006
Infliximab Resistance, Infusion Reactions Linked to Immune Complex Formation
RA patients who do not respond to infliximab are likely to have infliximab/anti-infliximab immune complexes due to high levels of human antichimeric antibodies, and very large immune complexes may play a role in infliximab infusion reactions....van der Laken CJ, et al. Ann Rheum Dis. 2006; epub ahead of print.
Tuesday Jun 27, 2006
Bosentan Prevents Digital Ulcers, Improves Heart Function in Systemic Sclerosis
Bosentan reduces digital ulcer risk and improves heart function in systemic sclerosis patients... Allanore Y, et al. Presented at: EULAR 2006 Meeting; June 21–34, 2006; Amsterdam, The Netherlands. Abstract OP0120.
Tuesday Jun 27, 2006
Ultrasound Recommended for Long-Term Monitoring of RA Treatment Response
Ultrasound (US) and magnetic resonance imaging (MRI) surpass conventional radiography for detecting clinical improvement and regression of synovitis in RA finger joints, and musculoskeletal US provides the most cost-effective routine monitoring of disease activity and treatment response. Scheel AK, et al. Ann Rheum Dis. 2006;65:595–600.
Saturday Jun 24, 2006
New Imaging Methods Show Ligament Damage Is the First Stage of Hand OA
New, high-resolution MRI and PET imaging are bringing the details of hand OA into focus, and show that changes in ligaments are the first signs of disease... Tan AL. 2006 EULAR Meeting; June 21–24, 2006; Amsterdam, the Netherlands. Abstract SP0060.
Monday Jun 19, 2006
EULAR Issues First Gout Guidelines in Advance of Annual Meeting
The EULAR Gout Task Force has issued a two-part set of evidence-based recommendations for the diagnosis and management of gout... Zhang W, et al. Ann Rheum Dis [serial online]; 17 May 2006.
Monday Jun 19, 2006
Ultrasound Recommended for Long-Term Monitoring of RA Treatment Response
Ultrasound and magnetic resonance imaging surpass conventional radiography for detecting clinical improvement and regression of synovitis in RA finger joints, and musculoskeletal ultrasound likely provides the most cost-effective routine monitoring of disease activity and treatment response... Scheel AK, et al. Ann Rheum Dis. 2006;65:595-600.
Wednesday Jun 14, 2006
MRI Reveals Little in Low Back Pain
Routine use of MRI in early episodes of low back pain is probably a mistake... Carragee E. Presented at: American Pain Society 25th Annual Meeting; May 3–6, 2006; San Antonio, Tex.
Monday Jun 05, 2006
PsA Enthesopathy As Cause of Plantar Fasciitis Responds to TNF Inhibitors
The TNF inhibitors infliximab and etanercept are both effective for the treatment of enthesopathy associated with psoriatic arthritis... Ritchlin CT. J Rheumatol. 15 May 2006; [Epub ahead of print]
Thursday May 25, 2006
Higher Strength MRI Reduces Need for Arthroscopy for Shoulder Injuries
MR imaging at 3.0 Tesla may be able to replace arthroscopy for diagnosing some types of shoulder cartilage damage... Magee TH, Willams DS. Presented at: American Roentgen Ray Society 106th Annual Meeting; April 30–May 5; Vancouver, BC. Abstract 52.
Monday May 15, 2006
Infliximab Cools Spinal Inflammation in AS
Six months of infliximab significantly reduced MRI-proven sites of spinal inflammation in patients with ankylosing spondylitis... Braun J, et al. Arthritis Rheum. 2006;54:1646-1652.
Thursday May 11, 2006
Adding Zoledronic Acid Improves MTX Efficacy in Early RA
Zoledronic acid added to standard methotrexate treatment reduced the progression of MRI hand and wrist erosions by 61% in patients with early RA, apparently by inhibiting osteoclast activity... Jarrett AJ, et al. Arthritis Rheum. 2006;54:1410-1414.
Thursday Apr 27, 2006
Rheumatologists Rely on Swollen Joint Counts When Deciding to Change RA Therapy
Rheumatologists rely on swollen joint count, morning stiffness, and CRP levels when deciding to change RA therapy... Soubrier M, et al. J Rheumatol. 2006 Apr 15; [Epub ahead of print]
Friday Mar 31, 2006
Targeted Liposomal Therapy Shows Promise in RA Animal Models
New research in rats suggests that arginine–glycine–aspartic acid (RGD) peptide liposomes that deliver dexamethasone phosphate directly to sites of inflammation show promise in the treatment of rheumatoid arthritis... Koning GA, et al. Arthritis Rheum. 2006;34:1198-1208.
Thursday Mar 30, 2006
Sodium Hyaluronate Effective in Chronic Shoulder Pain
Injections of sodium hyaluronate may be an effective and safe alternative to cyclooxygenase-2 inhibitors and other nonsteroidal anti-inflammatory drugs for the treatment of chronic shoulder pain... Blaine TA, et al. Presented at: 73rd Annual Meeting of the American Academy of Orthopaedic Surgeons; March 22–26, 2006; Chicago, Ill. Abstract 426.
Wednesday Mar 29, 2006
Synarc Granted Patent for Imaging Device to Increase the Accuracy of Cartilage Measurements by MRI and CT
Synarc, Inc, of San Francisco, California, announced the issuance of US patent No. 6,992,280 for a novel image calibration device...
Tuesday Mar 21, 2006
Spin-Lock (T1RHO) MRI May Be More Effective at Measuring Early Stages of Disc Degeneration
Spin-lock (T1RHO) magnetic resonance imaging may be more effective than other imaging technologies as a quantitative measure of early intervertebral disc degeneration... Johannessen W, et al. Presented at: 52nd Annual Meeting of the Orthopaedic Research Society; March 18–22, 2006; Chicago, Ill. Abstract 16.
Monday Mar 20, 2006
Single Injection of GDF-5 May Repair Degenerated Discs
A single injection of recombinant human growth and differentiation factor (GDF-5) may induce recovery of intravertebral disc height... Presented at: 52nd Annual Meeting of the Orthopaedic Research Society; March 18–22, 2006; Chicago, Ill. Abstract 14.
Tuesday Mar 14, 2006
Study Associates Meniscal Damage With Advanced Cartilage Loss in Early OA
Meniscal tears and malposition result in cartilage loss in patients with symptomatic knee osteoarthritis... Hunter DJ, et al. Arthritis Rheum. 2006;54:795-801.
Tuesday Feb 14, 2006
Disease Activity and Severity Seen as Determinants in Starting Tumor Necrosis Factor-Alpha Blockers in Ankylosing Spondylitis Prior to Publication of ASAS Recommendations
Both disease activity and severity were determinants in starting tumor necrosis factor-alpha blockers in ankylosing spondylitis patients prior to the publication of the 2003 Assessment in AS (ASAS) international working group recommendations... Pham T, et al. Ann Rheum Dis [serial online]. February 7, 2006; doi:10.1136/ard.2005.042630
Thursday Jan 19, 2006
Biomarkers Help Predict OA Patients at Greatest Risk of Progression
A single measurement of serum hyaluronic acid or short-term changes in urine C-telopeptide of type II collagen can identify osteoarthritis patients at the greatest risk of disease progression... Bruyere O, et al. Ann Rheum Dis. Published online January 5, 2006; doi:10.1136/ard.2005.045914.
Wednesday Dec 21, 2005
EMG May Be Better Than MRI at Diagnosing Spinal Stenosis
Because it can test nerve function and determine the presence of nerve damage, electromyogram testing may be more effective than magnetic resonance imaging in diagnosing spinal stenosis as well as detecting neuromuscular diseases that mimic stenosis... Haig AJ, et al. Spine. In press.
Wednesday Nov 16, 2005
TNF-α Antagonist Adalimumab Shows Promise in AS
Encouraging results from the ATLAS trial suggest that adalimumab and other TNF-α inhibitors may be effective in reducing the signs and symptoms of ankylosing spondylitis... Presented at: Annual Meeting of the American College of Rheumatology; November 12–17, 2005; San Diego, Calif.
Monday Oct 31, 2005
Regular Physical Activity May Strengthen Knee Cartilage
A novel magnetic resonance imaging technique used in a new study suggests that human articular cartilage can adapt to physical load, and that modest exercise improves knee cartilage glycosaminoglycan content in patients at risk for developing osteoarthritis … Roos EM, Dahlberg L. Arthritis Rheum. 2005;52:3507-3514.
Tuesday Oct 25, 2005
Combining X-Rays and MRIs Can Lead to Earlier Diagnosis of Spondyloarthritides
Combining data from X-rays and magnetic resonance imaging scans may lead to earlier detection of spondyloarthritides in patients presenting with recent-onset inflammatory back pain. Heuft-Dorenbosch L, et al. Ann Rheum Dis [serial online]. October 11, 2005.
Wednesday Sep 28, 2005
The XtremeCT May Be More Sensitive than DEXA in Predicting Fracture Risks
A new high-resolution imaging device, the XtremeCT, which measures both bone density and bone architecture, may have significant advantages over the current gold standard, dual-energy x-ray absorptiometry (DEXA)...Boutroy S, et al. Presented at: 27th Annual Meeting of the American Society for Bone and Mineral Research; September 23-27, 2005; Nashville, Tenn. Abstract SA360.
Tuesday Aug 23, 2005
MRI Data Show Etanercept Reduces Spinal Lesions in AS, but Questions Remain
Etanercept therapy leads to the regression of spinal lesions in active ankylosing spondylitis and undifferentiated spondyloarthritis... Rudwaleit M, et al. Ann Rheum Dis. 2005;64:1305-1310
Tuesday Aug 09, 2005
Neuropsychiatric Syndromes in SLE Patients Are Complex and Underdiagnosed
Though neuropsychiatric (NP) syndromes, regardless of etiology, are common among patients with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), a new study suggests that lupus patients with a history of NP syndromes report more severe anxiety and depression as well as cognitive dysfunction, pointing to the need for earlier diagnosis of these nonspecific symptoms...J Rheumatol. 2005;32:1459-1466.
Monday Jun 06, 2005
Trials Outline Effective Strategies for the Use of Existing Therapies in Ankylosing Spondylitis
Four new studies highlight ways to use non-steroidals, biologics, and methotrexate in ankylosing spondylitis. Marzo-Ortega H, et al. Ann Rheum Dis. 2005 May 26; [Epub ahead of print].
Friday Feb 25, 2005
Outpatient Arthroplasty May Become the Standard of Care
With minimally invasive surgical techniques, an increasing number of total joint replacement procedures can be performed on an outpatient basis...72nd Annual Meeting of the American Academy of Orthopaedic Surgeons; February 23, 2005
Friday Feb 25, 2005
New Findings Show Improved Outcomes With Arthroscopic Shoulder Stabilization
A new military study shows that arthroscopic shoulder stabilization performed through puncture wounds yields similar results with fewer complications and less operative time than traditional open surgery ... 72nd Annual Meeting of the American Academy of Orthopaedic Surgeons; February 23, 2005.
Thursday Jan 20, 2005
New Bone Imaging Technology May Give DEXA a Run for Its Money on Earth -- and in Space
New ultrasound bone imaging device, which measures bone strength and rate of bone loss as well as bone density, could become the standard for osteoporosis assessment... National Space Biomedical Research Institute, Houston, Texas.
Wednesday Oct 27, 2004
Anti-TNF Drugs Appear to Show Benefits in Most Ankylosing Spondylitis Patients and May Also Improve Psoriatic Arthritis
Recent study findings indicate that ankylosing spondylitis and psoriatic arthritis may respond well to infliximab, etanercept, and adalimumab... Rudwaleit M, Sieper J… Z Rheumatol. 2004;63:193-202.
Wednesday Oct 27, 2004
Anti-TNF Drugs Appear to Show Benefits in Most Ankylosing Spondylitis Patients – and May Also Improve Psoriatic Arthritis
Recent study findings indicate that ankylosing spondylitis and psoriatic arthritis may respond well to infliximab, etanercept, and adalimumab... Rudwaleit M, Sieper J… Z Rheumatol. 2004;63:193-202.
Monday Oct 18, 2004
MRI Has Modest Predictive Value in Detecting Response to TNF Therapy in Ankylosing Spondylitis
Treatment responders had a higher activity index on MRI than did nonresponders, but the difference was less marked than investigators expected... Rudwaleit M, Listing J, Brandt J, Braun J October 18, 2004, Sieper J. Prediction of a major clinical response (BASDAI 50) to TNF-alpha blockers in ankylosing spondylitis. Ann Rheum Dis. 2004; 63:665-670.
Monday Sep 20, 2004
Image-Guided Needle Placement's Contribution to Outcomes Questioned
Although image guidance improves the accuracy of needle placement, the practice has not been proven to improve outcomes. (Hall S, Buchbinder R. Ann Rheum Dis. 2004;63:1007-1008.)
Tuesday Aug 31, 2004
Primary Care Physician Survey Shows Back Pain Highly Prevalent, Often Involves Spasm
Acute back injuries often have a spasmodic as well as an inflammatory component; treating both expedites recovery.
Monday Aug 30, 2004
Incidence of Gout Increasing; New Therapies Have Promise to Make Disease More Manageable
(Bieber JD, Terkeltaub RA, et al. Arthritis Rheum. 2004;50:2400-2414.)
Thursday Jun 10, 2004
Preliminary TARGET Data Show Less GI Risk with Lumiracoxib Compared to Conventional NSAIDs
Early findings of a study show that patients who receive lumiracoxib for arthritis symptoms are 50 percent less likely to experience adverse GI effects than those who are treated with conventional NSAIDs.
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